
Gemfibrozil is available as an FDA-approved commercial tablet and as a compounded formulation, prepared by Mixlab for veterinary use in dogs. Available by prescription.
The uses and pharmacology described below reflect the FDA-approved labeling for this active ingredient; your veterinarian determines whether and how they apply to your animal's treatment plan.
Gemfibrozil is a fibrate that lowers triglyceride levels. On the FDA-approved human label, it is indicated for the treatment of severe hypertriglyceridemia.
In veterinary medicine, gemfibrozil is used off-label in dogs with hypertriglyceridemia, a condition seen more often in certain breeds such as Miniature Schnauzers. This information is not a substitute for veterinary diagnosis, prescribing, or monitoring. Compounded drugs are not approved by the FDA for safety or effectiveness.
Give with food. Commonly reported effects include vomiting and decreased appetite; muscle pain has also been reported in some cases. Your veterinarian will likely recheck bloodwork periodically to monitor triglyceride levels and response to treatment. Dietary fat restriction is often used together with this medication — follow your veterinarian's dietary recommendations.
Yes. Gemfibrozil is available only by prescription from a licensed veterinarian.
Both. Mixlab can dispense the FDA-approved commercial tablet, or compound the active ingredient into an alternative strength or format if your veterinarian determines that better suits your dog's needs. The decision rests with the prescribing veterinarian.
Gemfibrozil is used to help lower elevated triglyceride levels in dogs. Your veterinarian determines whether it's appropriate based on bloodwork.
Contact your veterinarian if you notice persistent vomiting, decreased appetite, or muscle soreness.