ChlorPHENIRAMINE Maleate Transdermal Pen (9mL)
ChlorPHENIRAMINE Maleate is a compounded formulation containing ChlorPHENIRAMINE Maleate, prepared by Mixlab for veterinary use. Available by prescription.
A transdermal pen is a simple way to give your pet medicine through their skin—usually used for cats by applying gel to the inside of their ear.
Step-by-Step:
- Get the pen ready – Twist the pen to dispense a small amount of gel. If it’s your first time, you will need to “prime” it first (the gel should be flush with the edge of the tip)
- Wear gloves – Always use a disposable glove or finger cot so the medication doesn’t absorb into your skin.
- Twist to dose – Follow the pen’s directions (like two full twists) to get the right amount of gel out. Always click in a clockwise direction, clicking counter-clockwise will stop you
- Pick the spot – Apply to a hairless area, usually the inside of your cat’s ear. Make sure the area is clean and dry.
- Apply the gel – Dab the gel directly with the pen or use your gloved finger to rub it in gently. Avoid the ear canal.
- Let it dry – It usually dries in a minute or two. Try to keep your pet from rubbing it off.
- Recap the pen – This keeps the medication fresh.
- Wash your hands – Even if you wore gloves, wash thoroughly after.
- Reward your pet – A treat helps make it a stress-free routine!
- Store properly – Keep at room temp, away from sunlight. Track doses so you know when it’s time to refill.
Important: Only apply where your vet has directed—usually hairless areas. Never apply over fur or broken skin. Keep other pets from licking the area until it’s dry.
The uses and pharmacology described below reflect the FDA-approved labeling for this active ingredient; your veterinarian determines whether and how they apply to your animal's treatment plan.
Chlorpheniramine utilizes a first-generation antihistamine strategy to manage allergic symptoms. It is frequently considered for pets presented with environmental allergies or mild itching.
Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring. Compounded drugs are not approved by the FDA for safety or effectiveness.
Commonly observed effects following the administration of chlorpheniramine include sedation or drowsiness, which is a characteristic of first-generation antihistamines. In some patients, particularly cats, localized digestive changes such as decreased appetite, vomiting or diarrhea have been noted. Some animals may exhibit paradoxical excitement or irritability rather than sedation. Owners should monitor their pet for any unusual behavioral shifts or changes in coordination and contact their veterinarian promptly with any concerns.
This medication is typically used with extra caution or avoided in patients with known glaucoma, severe cardiovascular disease, urinary retention or certain types of intestinal obstruction. Because chlorpheniramine has anticholinergic properties, it may influence tear production or heart rate, so a thorough review of existing conditions is essential. Significant interactions can occur if this antihistamine is administered concurrently with other central nervous system depressants or specific prescriptions used for behavioral management. Your veterinarian is the right person to provide guidance on the necessary duration of use and to monitor for any long-term effects.
Yes. While chlorpheniramine is available in various over-the-counter formats for humans, the specific concentrations and formulations used for pets require a valid prescription from a licensed veterinarian. Mixlab ensures all prescription requirements are met before dispensing any medication for your pet.
Yes. When a veterinarian determines that a customized strength or a specific dosage form—such as a flavored oral liquid or a chewable may be considered for—is necessary for an individual patient, Mixlab’s compounding team can prepare that formulation. The decision to use a commercial or compounded product rests with the prescribing veterinarian.
Sedation is a commonly observed effect of first-generation antihistamines like chlorpheniramine maleate. While some pets may appear noticeably more relaxed or tired after a dose, your veterinarian will monitor the degree of sedation to ensure it remains within a safe and appropriate clinical range.
If you observe significant lethargy, loss of appetite or unexpected hyperactivity, you should contact your veterinarian immediately. It is important to report any changes in your pet’s behavior or physical state so your veterinarian can evaluate if the management approach should be adjusted.
