
Zafirlukast is an FDA-approved commercial tablet containing zafirlukast, dispensed by Mixlab for veterinary use in dogs. Available by prescription.
"The uses and pharmacology described below reflect the FDA-approved labeling for this active ingredient; your veterinarian determines whether and how they apply to your animal's treatment plan.
Zafirlukast is a leukotriene receptor antagonist that blocks inflammatory mediators involved in airway constriction. On the FDA-approved human label, it is indicated for the prophylaxis and chronic treatment of asthma.
In veterinary medicine, published experience with zafirlukast is limited — the clearest documented use is a single case report describing management of refractory cough in a dog with chronic bronchitis. Your veterinarian determines whether this medication is appropriate for your pet's specific respiratory condition. Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing, or monitoring."
Reported effects in humans include headache and gastrointestinal upset; veterinary safety data is limited. This drug can interact with other medications metabolized by the liver, including certain anticoagulants — tell your veterinarian about all other medications your pet is taking. Use only under close veterinary supervision given the limited veterinary experience with this drug.
Yes. Zafirlukast is available only by prescription from a licensed veterinarian.
The active ingredient has an FDA-approved human label. Mixlab dispenses the commercial tablet under a licensed veterinarian's prescription for use in your dog.
Zafirlukast has been used to help manage chronic respiratory conditions in dogs. Published veterinary experience is limited, so your veterinarian will determine whether it is appropriate for your pet's specific case.
Contact Mixlab to discuss your patient's specific needs — compounding options are evaluated case by case.