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Silvadene (Silver Sulfadiazine) Cream

Silvadene (Silver Sulfadiazine) Cream

Rx approval required
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Select Strength: 1%
Select size: 50g Tube
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Silvadene (Silver Sulfadiazine) is an FDA-approved commercial topical product, dispensed by Mixlab for veterinary use in dogs, cats and horses. Available by prescription.

How to Apply Topical Cream to Your Pet

Topical creams are smooth, lotion-like medications applied to your pet’s skin to treat infections, wounds, or deliver medicine. Here’s a simple step-by-step guide:

  1. Prep Yourself: Wash your hands first. Use gloves if advised by your vet.
  2. Prep the Area: Clean the affected area gently with warm water and pat dry. If needed, part or trim fur to reach the skin (only if your vet recommends).
  3. Apply the Cream: Use the prescribed amount (usually pea-sized). Apply directly to the skin.
  4. Spread It Gently: Rub the cream in softly to create a thin, even layer.
  5. Prevent Licking: Distract your pet or use a cone to stop licking until the cream absorbs.
  6. Clean Up: Wash your hands (and discard gloves, if used).
  7. Follow-Up: Reward your pet! Monitor the area and contact your vet if irritation appears.

The uses and pharmacology described below reflect the FDA-approved labeling for this active ingredient; your veterinarian determines whether and how they apply to your animal's treatment plan.

Silver sulfadiazine is a topical antimicrobial that releases silver ions active against a range of bacteria and some fungi. On the FDA-approved human label, it is indicated to help prevent and treat infection in burn wounds.

In veterinary medicine, silver sulfadiazine is used off-label in dogs, cats and horses for topical wound care and localized skin infections. This information is not a substitute for veterinary diagnosis, prescribing, or monitoring.

Apply only to the areas directed by your veterinarian, and avoid contact with the eyes. Clean the area gently before each application as directed. Cats can be more sensitive to sulfa-containing products, so use only under veterinary direction, and never apply over a larger area than instructed. Contact your veterinarian if the treated area appears to worsen, or if your pet licks or scratches at it excessively.

Do I need a prescription for Silvadene?

Yes. Silvadene is available only by prescription from a licensed veterinarian.

Is Silvadene an FDA-approved product?

The active ingredient has an FDA-approved human label. Mixlab dispenses the commercial topical product under a licensed veterinarian's prescription for use in your animal.

What is Silvadene used for in animals?

Silvadene is used topically to help manage wound care and localized skin infections in dogs, cats and horses. Your veterinarian determines whether it's appropriate for your animal's specific wound.

Can this be compounded in a different strength or form?

Contact Mixlab to discuss your patient's specific needs — compounding options are evaluated case by case.

Mixlab is a licensed veterinary pharmacy dispensing both compounded and commercial medications, operating under the oversight of licensed pharmacists and in compliance with applicable state and federal pharmacy regulations. Compounded medications are prepared in compliance with USP standards and under PCAB-accredited practices. All medications dispensed by Mixlab require a valid prescription from a licensed veterinarian.
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