Phytonadione (Vitamin K1) Oral Solution
Phytonadione (Vitamin K1) is a compounded formulation containing Vitamin K1, prepared by Mixlab for veterinary use. Available by prescription.
How to Give Oral Solution
Oral solutions are liquid medications that you give by mouth. In a solution, the medication is completely dissolved in the liquid, so it usually looks clear or evenly colored. Here's how to give it:
- Shake well each time to mix the medication (5-10 seconds).
- Measure the dose using the syringe/dropper provided or one recommended by your vet. Insert the top of the oral syringe into the bottle adapter. Turn the bottle upside down and pull the plunger until the medicine reaches the volume required
- Hold your pet steady: a towel or helper can assist with squirmy pets.
- Administer the dose slowly into the side of the mouth. Allow small pauses if needed for swallowing.
- Raise the head slightly to help the medication go down and clean any spills with a little water or tissue.
- Praise your pet and offer a treat or water (unless advised against feeding right after).
- Clean the syringe with water immediately after use. Store the bottle as directed, out of sunlight.
- Consistency is key: Shake each time, measure accurately, and contact your vet if any issues arise.
The uses and pharmacology described below reflect the FDA-approved labeling for this active ingredient; your veterinarian determines whether and how they apply to your animal's treatment plan.
Phytonadione, also known as Vitamin K1, is a fat-soluble vitamin utilized in veterinary medicine for its role in supporting coagulation. It is a prescription medication available for use in multiple species, requiring professional guidance from a licensed veterinarian. It is frequently considered in the context of emergency care for patients presented with anticoagulant rodenticide ingestion or specific liver-related bleeding challenges.
Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring. Compounded drugs are not approved by the FDA for safety or effectiveness.
At a pharmacological level, it provides a source of a nutrient required for the synthesis of coagulation factors II, VII, IX and X in the liver. Commonly observed effects are typically rare but may include localized changes at the injection site or temporary digestive shifts if given orally. Because it influences blood clotting, your veterinarian will monitor for observational signs of recovery through periodic coagulation tests (PT/PTT). Owners should monitor for any unusual bruising or lethargy and contact their veterinarian promptly with any concerns.
Yes. Professional strength Vitamin K1 is a prescription medication and requires a valid authorization from a licensed veterinarian. Mixlab ensures all requirements are met before preparing any medication.
Yes. Mixlab specializes in compounding phytonadione into customized flavored oral formats, such as flavored oral liquids or treats, to support easier administration during the recovery process.
Veterinarians discuss Vitamin K1 because many rodenticides are considered to interfere with the body's natural Vitamin K cycle, leading to impaired blood clotting. Supplementation provides a method for supporting the risk management of internal bleeding.
Vitamin K1 is considered to be better absorbed when given with a meal containing some fat. Your veterinarian will provide specific guidance on the most appropriate administration schedule for your pet.
Rodenticides may remain in the body for several weeks. Your veterinarian will determine the necessary duration based on the specific toxin ingested and follow-up blood work results.
