PhenylPROPANOLAMINE HCL Transdermal Pen (9mL)
PhenylPROPANOLAMINE HCL is a compounded formulation containing PhenylPROPANOLAMINE HCL, prepared by Mixlab for veterinary use. Available by prescription.
A transdermal pen is a simple way to give your pet medicine through their skin—usually used for cats by applying gel to the inside of their ear.
Step-by-Step:
- Get the pen ready – Twist the pen to dispense a small amount of gel. If it’s your first time, you will need to “prime” it first (the gel should be flush with the edge of the tip)
- Wear gloves – Always use a disposable glove or finger cot so the medication doesn’t absorb into your skin.
- Twist to dose – Follow the pen’s directions (like two full twists) to get the right amount of gel out. Always click in a clockwise direction, clicking counter-clockwise will stop you
- Pick the spot – Apply to a hairless area, usually the inside of your cat’s ear. Make sure the area is clean and dry.
- Apply the gel – Dab the gel directly with the pen or use your gloved finger to rub it in gently. Avoid the ear canal.
- Let it dry – It usually dries in a minute or two. Try to keep your pet from rubbing it off.
- Recap the pen – This keeps the medication fresh.
- Wash your hands – Even if you wore gloves, wash thoroughly after.
- Reward your pet – A treat helps make it a stress-free routine!
- Store properly – Keep at room temp, away from sunlight. Track doses so you know when it’s time to refill.
Important: Only apply where your vet has directed—usually hairless areas. Never apply over fur or broken skin. Keep other pets from licking the area until it’s dry.
The uses and pharmacology described below reflect the FDA-approved labeling for this active ingredient; your veterinarian determines whether and how they apply to your animal's treatment plan.
Phenylpropanolamine hydrochloride (PPA) is a sympathomimetic agent utilized extensively in veterinary medicine for its ability to influence smooth muscle tone. It is a prescription medication available for use in dogs, requiring professional guidance from a licensed veterinarian. It is frequently considered in the context of urinary health for patients presented with urethral sphincter mechanism incompetence (USMI).
Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring. Compounded drugs are not approved by the FDA for safety or effectiveness.
At a pharmacological level, it is considered to influence the release of norepinephrine to stimulate alpha-adrenergic receptors in the bladder neck and urethra. Commonly observed effects include behavioral shifts such as restlessness, irritability or increased thirst and cardiovascular changes like an increased heart rate. Because it influences blood pressure, your veterinarian will monitor for observational signs of hypertension. Owners should monitor for significant changes in appetite or energy and contact their veterinarian promptly with any concerns.
Yes. Phenylpropanolamine is a prescription medication and requires a valid authorization from a licensed veterinarian. Mixlab verifies all legal requirements before any medication is prepared.
Yes. Mixlab specializes in compounding phenylpropanolamine into customized strengths and flavored oral formats, such as flavored oral liquids or treats, to support easier administration for your dog.
Veterinarians discuss PPA because it is considered to influence the muscle tone of the urethral sphincter. By influencing the strength of these muscles, it provides a method for addressing involuntary urine leakage in dogs.
Important observational signs include unusual restlessness, a racing heart or a decrease in appetite. If you notice these behavioral shifts, contact your veterinarian immediately for a clinical review.
PPA may influence blood pressure and heart rate. Your veterinarian will determine if this management approach is appropriate for your individual pet based on their cardiovascular health history.
