NexGard® COMBO Topical
NexGard® COMBO is an FDA-approved preparation containing NexGard COMBO, for veterinary use. Available by prescription.
Esafoxolaner, eprinomectin and praziquantel, commercially available as NexGard® COMBO, is a broad-spectrum topical solution utilized for feline parasite management. It is a prescription medication requiring a valid veterinarian-client-patient relationship. It is frequently considered in the context of parasite prevention for cats at risk of fleas, ticks, heartworms and intestinal worms.
The actions described here reflect the product's FDA-approved labeling; your veterinarian determines the appropriate use for your animal.
Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring.
At a pharmacological level, it integrates three agents considered to influence the central nervous system of invertebrates and the cell membrane permeability of tapeworms. Commonly observed effects include localized changes at the application site like hair loss or redness and behavioral shifts like lethargy. Because it contains an isoxazoline, your veterinarian will monitor for observational signs of neurological shifts. Owners should monitor for significant changes in activity and contact their veterinarian promptly.
Yes. NexGard® COMBO is a prescription medication and requires a valid authorization from a licensed veterinarian. Mixlab verifies all legal requirements before dispensing.
Veterinarians discuss NexGard® COMBO for its ability to address fleas, ticks, heartworms, hookworms, roundworms and tapeworms. This provides a method for comprehensive monthly management in cats.
This is a topical solution applied to the skin at the base of the neck. Your veterinarian will provide professional guidance on the proper application technique to ensure the medication has adequate time to be absorbed.
Isoxazoline medications are associated with potential neurological signs in some patients. You should discuss your cat's health history with your veterinarian before starting this management approach.
NexGard® COMBO is designed for monthly administration. Your veterinarian will determine the necessary duration of use based on your cat's individual environmental risk factors.
