Neomycin/Polymyxin B/Dexamethasone Ophthalmic Ointment
Neomycin/Polymyxin B/Dexamethasone is a compounded formulation containing Neomycin, Polymyxin B, Dexamethasone, prepared by Mixlab for veterinary use. Available by prescription.
This compounded formulation combines active ingredients from different drug classes: neomycin, an aminoglycoside antibiotic; polymyxin B, a polymyxin antibiotic; and dexamethasone, a corticosteroid. In compounding practice, clinicians may consider a multi-ingredient preparation like this to address more than one aspect of a patient's physiology at once. Your veterinarian determines whether it is appropriate based on your animal's diagnostic findings.
This description reflects the general pharmacology of the active ingredient's drug class; your veterinarian determines whether this approach is appropriate for your animal.
Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring. Compounded drugs are not approved by the FDA for safety or effectiveness.
At a pharmacological level, the antibiotics are considered to influence the bacterial population while dexamethasone is considered to modulate the inflammatory response. Commonly observed effects include localized changes such as mild redness, temporary squinting or discharge. Because the formulation contains a corticosteroid, your veterinarian will monitor for observational signs of steroid influence. Ensuring the eardrum is intact is a high-priority clinical consideration before otic use. Owners should monitor for any behavioral shifts and contact their veterinarian promptly.
Yes. This combination requires a valid prescription from a licensed veterinarian before it can be dispensed. Mixlab verifies all legal authorizations before any medication is prepared or shipped.
Yes. Mixlab specializes in compounding neomycin, polymyxin B and dexamethasone into customized sterile eye drops or otic suspensions tailored to the specific needs of your pet.
Veterinarians may consider combining these ingredients so the preparation can act through more than one mechanism at once — here, it brings together antibacterial and anti-inflammatory actions in one preparation. Your veterinarian determines whether this multi-targeted approach is appropriate for your pet.
Steroids are typically avoided in pets with corneal ulcers as they may influence the healing process. Your veterinarian will perform a professional exam to ensure this management approach is appropriate.
You should monitor for observational signs like decreased redness and improved comfort. If you notice increased squinting or cloudiness, contact your veterinarian immediately for a clinical review.
