Neomycin/Polymyxin B/Dexamethasone clEARmix Lanolin Otic (3mL Syringe)
Neomycin/Polymyxin B/Dexamethasone is a compounded formulation containing Neomycin, Polymyxin B, Dexamethasone, prepared by Mixlab for veterinary use. Available by prescription.
How to Use clEARmix Lanolin Otic (Ear Medication)
This is a thick ear ointment used to treat ear infections. It comes in a pre-filled syringe with a soft tip, making it easier to apply and designed to stay in your pet’s ear longer.
Step-by-Step: 1. Warm the syringe – If it’s cold, hold it in your hands for a minute to soften the ointment. Do not microwave. 2. Position your pet – Have them sit in a comfy spot. You may need someone to gently help hold them. Lift their ear flap straight up. 3. Clean the ear (if needed) – Only if your vet told you to. Use a vet-approved ear cleaner and cotton ball—never a Q-tip deep in the ear. Let the ear dry. 4. Apply the medication – Remove the cap, then gently insert just the tip of the syringe into the ear opening. Don’t push in deep. 5. Dispense slowly – Press the plunger gently to apply the full dose or the amount your vet prescribed. 6. Massage the ear – Rub the base of the ear for about 30 seconds to help the medication spread. 7. Let them shake – It’s normal! Wipe off any excess with a tissue or cloth. 8. Reward your pet – Give them praise and maybe a treat to make it a positive experience. 9. Store the rest – If there’s more medication left, recap the syringe and store at room temp. Wash your hands after use.
This compounded formulation combines active ingredients from different drug classes: neomycin, an aminoglycoside antibiotic; polymyxin B, a polymyxin antibiotic; and dexamethasone, a corticosteroid. In compounding practice, clinicians may consider a multi-ingredient preparation like this to address more than one aspect of a patient's physiology at once. Your veterinarian determines whether it is appropriate based on your animal's diagnostic findings.
This description reflects the general pharmacology of the active ingredient's drug class; your veterinarian determines whether this approach is appropriate for your animal.
Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring. Compounded drugs are not approved by the FDA for safety or effectiveness.
At a pharmacological level, the antibiotics are considered to influence the bacterial population while dexamethasone is considered to modulate the inflammatory response. Commonly observed effects include localized changes such as mild redness, temporary squinting or discharge. Because the formulation contains a corticosteroid, your veterinarian will monitor for observational signs of steroid influence. Ensuring the eardrum is intact is a high-priority clinical consideration before otic use. Owners should monitor for any behavioral shifts and contact their veterinarian promptly.
Yes. This combination requires a valid prescription from a licensed veterinarian before it can be dispensed. Mixlab verifies all legal authorizations before any medication is prepared or shipped.
Yes. Mixlab specializes in compounding neomycin, polymyxin B and dexamethasone into customized sterile eye drops or otic suspensions tailored to the specific needs of your pet.
Veterinarians may consider combining these ingredients so the preparation can act through more than one mechanism at once — here, it brings together antibacterial and anti-inflammatory actions in one preparation. Your veterinarian determines whether this multi-targeted approach is appropriate for your pet.
Steroids are typically avoided in pets with corneal ulcers as they may influence the healing process. Your veterinarian will perform a professional exam to ensure this management approach is appropriate.
You should monitor for observational signs like decreased redness and improved comfort. If you notice increased squinting or cloudiness, contact your veterinarian immediately for a clinical review.
