Neomycin/Polymyxin B clEARmix Lanolin Otic (3mL Syringe)
Neomycin/Polymyxin B is a compounded formulation containing Neomycin, Polymyxin B, prepared by Mixlab for veterinary use. Available by prescription.
How to Use clEARmix Lanolin Otic (Ear Medication)
This is a thick ear ointment used to treat ear infections. It comes in a pre-filled syringe with a soft tip, making it easier to apply and designed to stay in your pet’s ear longer.
Step-by-Step: 1. Warm the syringe – If it’s cold, hold it in your hands for a minute to soften the ointment. Do not microwave. 2. Position your pet – Have them sit in a comfy spot. You may need someone to gently help hold them. Lift their ear flap straight up. 3. Clean the ear (if needed) – Only if your vet told you to. Use a vet-approved ear cleaner and cotton ball—never a Q-tip deep in the ear. Let the ear dry. 4. Apply the medication – Remove the cap, then gently insert just the tip of the syringe into the ear opening. Don’t push in deep. 5. Dispense slowly – Press the plunger gently to apply the full dose or the amount your vet prescribed. 6. Massage the ear – Rub the base of the ear for about 30 seconds to help the medication spread. 7. Let them shake – It’s normal! Wipe off any excess with a tissue or cloth. 8. Reward your pet – Give them praise and maybe a treat to make it a positive experience. 9. Store the rest – If there’s more medication left, recap the syringe and store at room temp. Wash your hands after use.
This compounded formulation combines neomycin, an aminoglycoside antibiotic, with polymyxin B, a polymyxin antibiotic — two different drug classes. In compounding practice, clinicians may consider a combination like this for a multi-targeted approach. Your veterinarian determines whether it is appropriate based on your animal's diagnostic findings.
This description reflects the general pharmacology of the active ingredient's drug class; your veterinarian determines whether this approach is appropriate for your animal.
Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring. Compounded drugs are not approved by the FDA for safety or effectiveness.
At a pharmacological level, neomycin is considered to influence protein synthesis while polymyxin B is considered to disrupt bacterial cell membranes. Commonly observed effects include localized changes such as mild redness, temporary discharge or increased sensitivity at the site of application. Ensuring the eardrum is intact is a high-priority clinical consideration before applying the medication to the ear canal. Owners should monitor for any unusual behavioral shifts and contact their veterinarian promptly with any concerns regarding the patient's response to the medication.
Yes. This combination requires a valid prescription from a licensed veterinarian before it can be dispensed. Mixlab verifies all professional authorizations before preparing any medication.
Yes. Mixlab specializes in compounding neomycin and polymyxin B into customized strengths and vehicles, such as specialized eye drops or ear suspensions, to suit the specific needs of your pet.
Veterinarians discuss this combination because the two agents are considered to influence different types of bacteria. This provides a method for addressing a broader spectrum of bacterial challenges than a single agent.
You should monitor for observational signs like decreased redness and improved comfort. If you notice your pet holding their head tilted or appearing dizzy, contact your veterinarian immediately for a clinical review.
Yes, this combination is frequently considered for feline ophthalmic needs. Your veterinarian will determine the appropriate frequency and duration based on your cat's specific diagnostic findings.
