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Lidocaine/Prilocaine Cream

Lidocaine/Prilocaine Cream

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Select Strength: 2.5/2.5%
Select size: 30g tube
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Lidocaine/Prilocaine is a compounded formulation containing Lidocaine, Prilocaine, prepared by Mixlab for veterinary use. Available by prescription.

How to Apply Topical Cream to Your Pet

Topical creams are smooth, lotion-like medications applied to your pet’s skin to treat infections, wounds, or deliver medicine. Here’s a simple step-by-step guide:

  1. Prep Yourself: Wash your hands first. Use gloves if advised by your vet.
  2. Prep the Area: Clean the affected area gently with warm water and pat dry. If needed, part or trim fur to reach the skin (only if your vet recommends).
  3. Apply the Cream: Use the prescribed amount (usually pea-sized). Apply directly to the skin.
  4. Spread It Gently: Rub the cream in softly to create a thin, even layer.
  5. Prevent Licking: Distract your pet or use a cone to stop licking until the cream absorbs.
  6. Clean Up: Wash your hands (and discard gloves, if used).
  7. Follow-Up: Reward your pet! Monitor the area and contact your vet if irritation appears.

This compounded formulation combines lidocaine, a local anesthetic, with prilocaine, a local anesthetic — two different drug classes. In compounding practice, clinicians may consider a combination like this for a multi-targeted approach. Your veterinarian determines whether it is appropriate based on your animal's diagnostic findings.

This description reflects the general pharmacology of the active ingredient's drug class; your veterinarian determines whether this approach is appropriate for your animal.

Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring. Compounded drugs are not approved by the FDA for safety or effectiveness.

At a pharmacological level, both lidocaine and prilocaine are considered for their role in managing the permeability of neuronal membranes to sodium ions, providing a method for blocking the conduction of nerve impulses. Commonly observed effects include localized changes such as temporary paleness (blanching), redness or mild swelling at the application site. Because systemic absorption is possible, your veterinarian will monitor for observational signs of sensitivity, particularly in pets with known hepatic or cardiovascular impairment. Owners should ensure the pet does not ingest the medication.

Do I need a prescription?

Yes. Lidocaine/prilocaine is a prescription medication and requires a valid authorization from a licensed veterinarian. Mixlab verifies all legal requirements before any medication is prepared or shipped.

Can this be compounded for my pet?

Yes. While available in commercial creams, Mixlab specializes in compounding lidocaine and prilocaine into customized strengths and flavored vehicles, such as specialized gels, to suit your pet's needs.

How long should the cream stay on the skin?

Veterinarians typically recommend a specific contact time, often under an occlusive dressing, to support absorption into the skin. Your veterinarian will provide guidance on the necessary duration for the procedural area.

Is it safe if my pet licks the cream?

You should manage your pet to prevent ingestion, as systemic absorption through the mouth can be associated with coordination changes or other shifts. Your veterinarian may recommend a protective collar during the application period.

What monitoring is required during use?

Your veterinarian will monitor the localized area for observational signs of recovery or sensitivity. If you notice persistent irritation or unusual behavioral shifts, contact your veterinarian promptly for a clinical review.

Mixlab is a licensed veterinary pharmacy dispensing both compounded and commercial medications, operating under the oversight of licensed pharmacists and in compliance with applicable state and federal pharmacy regulations. Compounded medications are prepared in compliance with USP standards and under PCAB-accredited practices. All medications dispensed by Mixlab require a valid prescription from a licensed veterinarian.
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