Diclazuril/Levamisole HCl/Elevate Powder
Diclazuril/Levamisole HCl/Elevate is a compounded formulation containing Diclazuril, Levamisole HCl, Elevate, prepared by Mixlab for veterinary use. Available by prescription.
Powder medications are meant to be mixed into food or treats, not given on their own (since most pets won’t lick up plain powder). The key is to mix it into something tasty so your pet eats the entire dose.
How to Give It:
- Measure the dose using the included scoop or follow the instructions. If you’re unsure how much to give, ask your vet or pharmacist.
- Mix it with a small amount of soft food or treat—like wet food, baby food (meat flavor), peanut butter (xylitol-free), yogurt, or cheese. Use just enough to hide the powder so your pet finishes it all in one go.
- Stir it well to blend the powder in evenly. Add a splash of water if needed to make it smoother.
- Offer it when your pet is a little hungry, and watch to make sure they eat the whole thing.
- If your pet refuses, try something else they love next time. For cats, you can also try smearing the paste on their paw to lick off (only if safe and comfortable).
- For large animals, mix the powder into a small portion of feed with water or molasses, then follow with the rest of their food once they’ve eaten the medicated part.
- Store the powder in a cool, dry place with the lid closed tightly.
Never give powder straight into your pet’s mouth—it can be dangerous if inhaled.
This compounded formulation combines active ingredients from different drug classes: diclazuril, an antiprotozoal; levamisole, an immunomodulator; and a vitamin E supplement. In compounding practice, clinicians may consider a multi-ingredient preparation like this to address more than one aspect of a patient's physiology at once. Your veterinarian determines whether it is appropriate based on your animal's diagnostic findings.
At a pharmacological level, the three components act through distinct yet complementary mechanisms. Diclazuril is a benzeneacetonitrile antiprotozoal that acts by disrupting specific stages of the parasite's life cycle, inhibiting its ability to replicate within the host. Levamisole HCl is frequently discussed in this context for its immunomodulatory properties, as it may influence the cellular immune response of the horse during a parasitic challenge. Elevate provides a specialized, water-soluble natural Vitamin E (d-alpha-tocopherol) that functions as a potent antioxidant. This component acts at a cellular level to support the protection of neurological tissues from oxidative stress, which is a significant clinical concern in neurological cases. Your veterinarian will determine if this specific combination is appropriate based on your horse's weight, neurological status and diagnostic findings.
This description reflects the general pharmacology of the active ingredient's drug class; your veterinarian determines whether this approach is appropriate for your animal.
Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring. Compounded drugs are not approved by the FDA for safety or effectiveness.
Commonly observed effects of this combination may include mild gastrointestinal changes such as loose stools, flatulence or a temporary decrease in appetite. In some horses receiving levamisole, owners may observe mild behavioral changes, restlessness or localized sweating shortly after administration. Because neurological conditions can be sensitive to physiological shifts, your veterinarian will monitor for any changes in coordination or alertness throughout the course of the prescription. If you observe significant changes in your horse's gait, stumbling or signs of physical distress, contact your veterinarian promptly to share these observations.
This medication is typically used with caution in pregnant or lactating mares, as the safety profile for developing foals has not been extensively characterized for all components. It is essential to provide your veterinarian with a complete history of all other supplements and medications your horse is receiving, as concurrent use can influence the overall metabolic profile. Your veterinarian is the best resource for designing a comprehensive approach to patient monitoring and support during the administration period. Always follow the professional guidance provided by your veterinarian regarding the duration of use and the timing of any necessary follow-up examinations.
Yes. This combination is a prescription medication and can only be dispensed by a licensed pharmacy upon receipt of a valid authorization from a licensed veterinarian. Mixlab verifies all prescriptions before any medication is prepared or sent to your home or stable.
Yes. Since this specific triple-combination is typically available as a compounded preparation, Mixlab can provide it in formats—such as flavored oral pastes or powders—that facilitate administration for your horse. Your veterinarian will determine the most appropriate compounded strength and format based on your animal's individual requirements.
Veterinarians may consider combining these ingredients so the preparation can act through more than one mechanism at once — here, it focuses on antiprotozoal action. Your veterinarian determines whether this multi-targeted approach is appropriate for your pet.
Owners should monitor for signs of gastrointestinal upset, such as loose manure or changes in appetite. You should also observe your horse’s general attitude and coordination, contacting your veterinarian if you notice any behavior that deviates from the horse's normal routine or signs of restlessness.
