Voriconazole Tablet
Voriconazole is available as an FDA-approved commercial tablet, injection, or oral suspension and as a compounded formulation, prepared by Mixlab for veterinary use in dogs, cats and horses. Available by prescription.
The uses and pharmacology described below reflect the FDA-approved labeling for this active ingredient; your veterinarian determines whether and how they apply to your animal's treatment plan.
Voriconazole is a triazole antifungal that inhibits a fungal enzyme needed for cell membrane synthesis. On the FDA-approved human label, it is indicated for invasive aspergillosis, candidemia, and serious infections caused by Scedosporium and Fusarium species in patients who cannot tolerate or do not respond to other therapy.
In veterinary medicine, voriconazole is used off-label in dogs, cats, and horses for serious systemic fungal infections. Cats require extra caution with this drug class, and your veterinarian will weigh the risks and benefits carefully for feline patients. This information is not a substitute for veterinary diagnosis, prescribing, or monitoring. Compounded drugs are not approved by the FDA for safety or effectiveness.
Regular liver enzyme testing is recommended during treatment, since hepatotoxicity has been reported. Vision changes, incoordination, and heart rhythm changes have also been reported, particularly in cats, which require close monitoring on this medication. Give on an empty stomach unless your veterinarian directs otherwise. Voriconazole has significant interactions with many other drugs due to its effect on liver metabolism enzymes — tell your veterinarian about all other medications your pet is taking. Avoid use in pregnant animals unless your veterinarian determines it is necessary.
Yes. Voriconazole is available only by prescription from a licensed veterinarian.
Both. Mixlab can dispense the FDA-approved commercial product, or compound the active ingredient into an alternative strength or format if your veterinarian determines that better suits your pet's needs. The decision rests with the prescribing veterinarian.
Voriconazole is used to treat serious systemic fungal infections in dogs, cats, and horses. Your veterinarian determines whether this antifungal is appropriate based on diagnostic testing.
Contact your veterinarian if you notice vomiting, loss of appetite, vision changes, incoordination, or lethargy. Periodic bloodwork is often recommended to monitor liver function.
