
TRILOstane is an FDA-approved preparation containing TRILOstane, for veterinary use. Available by prescription.
Use as directed by your veterinarian.
Trilostane is a synthetic steroid analogue utilized extensively in veterinary medicine for hormonal management. It is a prescription medication available for use in dogs, requiring professional guidance and frequent monitoring by a licensed veterinarian. It is frequently considered in the context of Cushing’s disease (hyperadrenocorticism) for managing the production of cortisol.
The actions described here reflect the product's FDA-approved labeling; your veterinarian determines the appropriate use for your animal.
Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring.
At a pharmacological level, it manages cortisol production by inhibiting the 3-beta-hydroxysteroid dehydrogenase enzyme system. Commonly observed effects include behavioral shifts such as lethargy, weakness or localized digestive changes like vomiting. Because it may influence adrenal function, your veterinarian will perform regular blood work (ACTH stimulation tests) to monitor your pet’s cortisol levels. Owners should monitor for significant changes in appetite or energy and contact their veterinarian promptly with any concerns.
Yes. Trilostane is a prescription medication and requires a valid authorization from a licensed veterinarian. Mixlab ensures all professional standards are met before dispensing.
Yes. Mixlab specializes in compounding trilostane into customized strengths and flavored oral formats, such as capsules or flavored oral liquids, to support easier administration for your pet.
Veterinarians discuss trilostane because it may reduce the excessive amount of cortisol the adrenal glands are producing. This offers an approach to managing the clinical signs of the disease.
Veterinarians recommend ACTH stimulation tests to monitor the physiological response to the medication. This offers an approach to ensuring the dose manages the condition while remaining safe.
You should monitor for observational signs like a decrease in thirst and urination. If your pet appears unusually weak or loses their appetite, contact your veterinarian immediately for a clinical review.