Sign up
Simplicef Tablet

Simplicef Tablet

Rx approval required
We'll contact your veterinarian to review your medication request. If you aren't sure of the correct size and dose, please contact them directly or get in touch with our team.
Select Strength: 100mg
Select count: 10 ea
Sign up
Are you a prescriber?
Login to our prescriber platform, eMix, to prescribe with Mixlab.

Simplicef is an FDA-approved preparation containing Simplicef, for veterinary use. Available by prescription.

Cefpodoxime proxetil, commercially available as Simplicef, is a third-generation cephalosporin antibiotic utilized extensively in veterinary medicine. It is a prescription medication available for use in dogs, requiring a valid veterinarian-client-patient relationship. It is frequently considered in the context of infectious diseases for patients presented with bacterial skin infections (pyoderma).

The actions described here reflect the product's FDA-approved labeling; your veterinarian determines the appropriate use for your animal.

Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring.

At a pharmacological level, it is used in the context of managing bacterial cell wall synthesis, providing an approach for managing susceptible gram-positive and gram-negative organisms. Commonly observed effects include localized digestive changes such as vomiting or diarrhea and behavioral shifts like lethargy. Because it manages the bacterial population, it is important to complete the entire course as directed. Owners should monitor for any signs of an allergic response and contact their veterinarian promptly with any concerns regarding the patient's response.

Do I need a prescription for Simplicef?

Yes. Simplicef is a prescription medication and requires a valid authorization from a licensed veterinarian. Mixlab verifies all professional authorizations before dispensing.

Can Simplicef be compounded for my dog?

Simplicef is a commercial tablet. If your dog requires a customized strength or a flavored oral liquid, Mixlab specializes in compounding the active ingredient, cefpodoxime, based on a valid prescription.

Why is this preferred for some skin infections?

Veterinarians discuss Simplicef because its mechanism is highly effective against common skin bacteria and often allows for once-daily dosing. This offers an approach to managing localized skin health during recovery.

Should I give this medication with food?

Simplicef is absorbed with or without food. However, giving it with a meal can help manage the risk of localized digestive upset in some dogs.

What signs of an allergy should I watch for?

Important observational signs include hives, swelling of the face or persistent vomiting. If you notice these shifts, contact your veterinarian immediately for a clinical review.

Mixlab is a licensed veterinary pharmacy dispensing both compounded and commercial medications, operating under the oversight of licensed pharmacists and in compliance with applicable state and federal pharmacy regulations. Compounded medications are prepared in compliance with USP standards and under PCAB-accredited practices. All medications dispensed by Mixlab require a valid prescription from a licensed veterinarian.
You may also like
We use cookies and similar technologies, including from analytics providers, to operate our site and understand how it's used. We do not sell your data or allow third-party advertising. See our Privacy Policy for details. Click "Reject" to decline non-essential cookies.