Rompun® (xylazine) Injectable

Giving your pet an injection might feel intimidating at first, but with practice, it becomes routine. Follow these steps for safe and stress-free injections.

Get Your Supplies Ready

1. Medication vial or pre-filled syringe
2. Alcohol swabs
3. Sterile syringe & needle (if not pre-filled)
4. Sharps container for safe needle disposal

Drawing Up the Dose (if needed)

1. Clean the vial top with an alcohol swab
2. Attach needle to syringe
3. Pull in air equal to the dose
4. Insert needle into vial, push air in
5. Draw out the correct dose
6. Tap out air bubbles

Pick the Injection Site

1. Subcutaneous (under the skin): Loose skin between shoulder blades or side
2. Intramuscular (into muscle): As directed by your vet

Prep the Area

1. Pinch a fold of skin to form a “tent” (for subcutaneous). Wipe with alcohol if recommended.

Inject the Medication

1. Hold the syringe like a pencil
2. Insert the needle into the base of the skin tent at a 45° angle
3. Push the plunger slowly to inject

After the Injection

1. Remove the needle smoothly
2. Place it immediately in the sharps container (don’t recap)
3. Pat the area and give your pet praise or a treat

Safety Tips

1. Never reuse needles
2. Always dispose of used needles properly
3. Ask your vet for help if unsure

Rompun is an FDA-approved injectable product containing xylazine, an alpha-2 adrenergic agonist used for sedation, muscle relaxation and analgesia. According to the FDA-approved labeling, it is used in animals such as horses and cattle; your veterinarian determines the appropriate use and dose.

Xylazine stimulates central alpha-2 adrenergic receptors, reducing the release of norepinephrine and producing a dose-dependent sedative and muscle-relaxant effect.

The actions described here reflect the product's FDA-approved labeling; your veterinarian determines the appropriate use for your animal.

Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring.

Rompun is administered by a veterinarian, who monitors the animal during sedation. It affects heart rate, blood pressure and gastrointestinal motility, and is used with caution in animals with certain cardiovascular or systemic conditions. Provide a complete history of other medications before use. Always consult your veterinarian about the appropriate duration of use and whether your horse's competitive status requires a withdrawal period. Xylazine (a sedative) is subject to detection in equine medication-testing programs and specific withdrawal times vary by jurisdiction and governing body.