
ReBalance® Antiprotozoal is an FDA-approved oral suspension prescribed for the treatment of Equine Protozoal Myeloencephalitis (EPM) in horses. It combines sulfadiazine and pyrimethamine, two antimicrobial agents that work synergistically to inhibit folic acid synthesis in the causative parasite, Sarcocystis neurona. This targeted therapy is utilized to halt the progression of the protozoal infection within the horse's central nervous system.
ReBalance is an FDA-approved oral suspension for horses containing sulfadiazine and pyrimethamine. According to the FDA-approved labeling, it is indicated for the treatment of equine protozoal myeloencephalitis (EPM) caused by Sarcocystis neurona. Your veterinarian determines the appropriate use and dose for your horse.
Sulfadiazine and pyrimethamine act on sequential steps of the folate pathway that susceptible protozoa require, disrupting their replication.
The actions described here reflect the product's FDA-approved labeling; your veterinarian determines the appropriate use for your animal.
Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring.
ReBalance is given orally for the extended course your veterinarian prescribes. Because folate-pathway inhibitors can affect blood cell production, your veterinarian may monitor blood counts during treatment. Report lethargy, pale gums or changes in appetite promptly.
Yes. This is a prescription product and can only be dispensed by a licensed pharmacy after a valid prescription is received from a licensed veterinarian. Mixlab verifies every prescription before dispensing.
EPM treatment courses are often extended over several weeks or longer. Follow your veterinarian's plan.
Your veterinarian may monitor blood counts, since this combination can affect blood cell production.
ReBalance is FDA-approved for the treatment of EPM caused by Sarcocystis neurona in horses.




