
Propafenone is an FDA-approved commercial product, dispensed by Mixlab for veterinary use in dogs. Available by prescription.
The uses and pharmacology described below reflect the FDA-approved labeling for this active ingredient; your veterinarian determines whether and how they apply to your animal's treatment plan.
Propafenone is a class IC antiarrhythmic that slows electrical conduction in the heart. On the FDA-approved human label, it is indicated for certain life-threatening ventricular arrhythmias and some supraventricular arrhythmias.
In veterinary medicine, propafenone has been studied and used off-label in dogs for certain arrhythmias, though it is used less often than other antiarrhythmic options. This information is not a substitute for veterinary diagnosis, prescribing, or monitoring.
This medication is generally started and monitored closely by a veterinary cardiologist or under direct veterinary supervision, often with periodic ECG monitoring. Commonly reported effects include decreased appetite, lethargy, and gastrointestinal upset; it can also worsen certain existing heart rhythm problems, so close monitoring is important. Tell your veterinarian about all other medications your dog is taking, since propafenone has significant drug interactions.
Yes. Propafenone is available only by prescription from a licensed veterinarian.
The active ingredient has an FDA-approved human label. Mixlab dispenses the commercial product under a licensed veterinarian's prescription for use in your dog.
Propafenone is used for certain heart rhythm abnormalities in dogs. Your veterinarian, often in consultation with a veterinary cardiologist, determines whether it's appropriate for your dog.
Contact Mixlab to discuss your patient's specific needs — compounding options are evaluated case by case.




