PredniSOLONE/Theophylline Oral Suspension (Anhydrous)
Prednisolone is a glucocorticoid that as an anti-inflammatory agent and is used in combination with Theophylline primarily for its bronchodilatory effects and to reduce coughing.
How to Give Anhydrous Oral Suspension
Oral Suspension (Anhydrous) is a liquid medication that does not contain water in its base. This might be an oil-based or other special base to help stabilize the medicine. It will look like a regular liquid medication, but often needs a good shake because the drug can settle. Here's how to give it:
- Shake well each time to mix the medication (5-10 seconds).
- Measure the dose using the syringe/dropper provided or one recommended by your vet. Insert the top of the oral syringe into the bottle adapter. Turn the bottle upside down and pull the plunger until the medicine reaches the volume required
- Hold your pet steady: a towel or helper can assist with squirmy pets.
- Administer the dose slowly into the side of the mouth. Allow small pauses if needed for swallowing.
- Raise the head slightly to help the medication go down and clean any spills with a little water or tissue.
- Praise your pet and offer a treat or water (unless advised against feeding right after).
- Clean the syringe with water immediately after use. Store the bottle as directed, out of sunlight.
- Consistency is key: Shake each time, measure accurately, and contact your vet if any issues arise.
This compounded formulation combines prednisolone, a corticosteroid, with theophylline, a bronchodilator — two different drug classes. In compounding practice, clinicians may consider a combination like this for a multi-targeted approach. Your veterinarian determines whether it is appropriate based on your animal's diagnostic findings.
This description reflects the general pharmacology of the active ingredient's drug class; your veterinarian determines whether this approach is appropriate for your animal.
Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring. Compounded drugs are not approved by the FDA for safety or effectiveness.
At a pharmacological level, prednisolone manages localized inflammation while theophylline is used in the context of managing smooth muscle relaxation in the airways and managing the diaphragm's strength. Commonly observed effects include behavioral shifts such as increased thirst, increased urination and temporary restlessness or gastrointestinal shifts like vomiting. Because theophylline may influence cardiovascular and neurological signaling, your veterinarian will monitor for observational signs of sensitivity. Owners should monitor for significant changes in appetite or energy and contact their veterinarian promptly with any concerns.
Yes. This combination requires a valid prescription from a licensed veterinarian before it can be dispensed. Mixlab verifies all legal requirements before any medication is prepared.
Yes. Mixlab specializes in compounding prednisolone and theophylline into customized strengths and flavored oral formats, such as flavored oral liquids or treats, to support easier administration.
Veterinarians discuss this combination for complex respiratory cases where managing both the inflammatory response and the diameter of the airways is a clinical objective. This offers an approach to managing lung health comprehensively.
Restlessness, shaking or an increased heart rate are common observations with methylxanthines like theophylline. Your veterinarian will provide guidance on how to monitor your pet's comfort and activity during use.
Giving this combination with food can often help manage the risk of localized digestive upset. Your veterinarian will provide specific guidance on the most appropriate administration schedule for your individual pet.
