
Nexgard Plus is an FDA-approved preparation containing Nexgard Plus, for veterinary use. Available by prescription.
Afoxolaner, moxidectin and pyrantel, commercially available as Nexgard Plus, is a combination anthelmintic and insecticide utilized for canine parasite management. It is a prescription medication available for use in dogs, frequently considered in the context of preventative health for patients at risk of heartworms and external parasites.
The actions described here reflect the product's FDA-approved labeling; your veterinarian determines the appropriate use for your animal.
Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring.
At a pharmacological level, these three agents are considered to influence the nervous systems of various parasites to provide a method for addressing heartworms, fleas, ticks and intestinal worms. Commonly observed effects include localized digestive changes such as vomiting or diarrhea. A high-priority clinical consideration is the association of isoxazolines with potential neurological shifts. Owners should monitor for any unusual tremors or coordination changes and contact their veterinarian promptly.
Yes. Nexgard Plus is a prescription medication and requires a valid authorization from a licensed veterinarian. Mixlab verifies professional authorization before preparing any medication.
Veterinarians discuss Nexgard Plus because it adds moxidectin and pyrantel to the afoxolaner. This provides a method for addressing heartworms and intestinal worms in addition to fleas and ticks.
Veterinarians perform a blood test before authorizing heartworm prevention to ensure no adult worms are present. Administering prevention to a heartworm-positive dog may lead to severe clinical complications.
Nexgard Plus is designed for monthly administration. Your veterinarian will determine the necessary duration of use based on your dog's environmental risk factors.
While the dose of moxidectin is considered to be within a safe range for most dogs, you should discuss your dog's breed and history with your veterinarian before starting any new management approach.




