Neo-Predef w/ Tetracaine Powder

Powder medications are meant to be mixed into food or treats, not given on their own (since most pets won’t lick up plain powder). The key is to mix it into something tasty so your pet eats the entire dose.

How to Give It:

1. Measure the dose using the included scoop or follow the instructions. If you’re unsure how much to give, ask your vet or pharmacist.
2. Mix it with a small amount of soft food or treat—like wet food, baby food (meat flavor), peanut butter (xylitol-free), yogurt, or cheese. Use just enough to hide the powder so your pet finishes it all in one go.
3. Stir it well to blend the powder in evenly. Add a splash of water if needed to make it smoother.
4. Offer it when your pet is a little hungry, and watch to make sure they eat the whole thing.
5. If your pet refuses, try something else they love next time. For cats, you can also try smearing the paste on their paw to lick off (only if safe and comfortable).
6. For large animals, mix the powder into a small portion of feed with water or molasses, then follow with the rest of their food once they’ve eaten the medicated part.
7. Store the powder in a cool, dry place with the lid closed tightly.

Never give powder straight into your pet’s mouth—it can be dangerous if inhaled.

Neomycin, isoflupredone and tetracaine, commercially available as Neo-Predef, is a topical antibiotic, corticosteroid and anesthetic powder utilized for localized management. It is a prescription medication available for use in dogs, cats and horses, requiring professional guidance from a licensed veterinarian. It is frequently considered in the context of dermatological challenges for patients presented with superficial wounds or "hot spots."

The actions described here reflect the product's FDA-approved labeling; your veterinarian determines the appropriate use for your animal.

Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring.

At a pharmacological level, neomycin is considered to influence bacteria, isoflupredone is considered to modulate inflammation and tetracaine is considered to influence sodium channels in association with topical numbing. Commonly observed effects include localized changes such as temporary paleness or mild redness at the application site. Because it acts as a powder, it is considered to support moisture management in the localized area. Owners should manage their pet to prevent ingestion of the powder. Contact your veterinarian promptly if you notice persistent irritation or unusual behavioral shifts. Always consult your veterinarian about the appropriate duration of use and whether your horse's competitive status requires a withdrawal period. Isoflupredone (a corticosteroid) and tetracaine (a local anesthetic) are subject to detection in equine medication-testing programs and specific withdrawal times vary by jurisdiction and governing body.