MKBM™ Kit (Sedation & Reversal) (Medetomidine/Ketamine/Butorphanol/Midazolam 20/100/30/20 mg/ml 10ml vial + Atipamezole 40mg/ml 30ml vial + Naltrexone 50mg/ml 10ml vial) Kit
MKBM™ Kit (Sedation & Reversal) is a compounded sedation-and-reversal kit containing Medetomidine, Ketamine, Butorphanol and Midazolam, with Atipamezole and Naltrexone provided as reversal agents, prepared by Mixlab for veterinary use. Available by prescription.
Use as directed by your veterinarian.
This is a compounded kit combining Medetomidine (an alpha-2 adrenergic agonist), Ketamine (a dissociative anesthetic), Butorphanol (an opioid analgesic) and Midazolam (a benzodiazepine), together with Atipamezole (an alpha-2 antagonist reversal agent) and Naltrexone (an opioid antagonist reversal agent). In compounding practice, clinicians may consider a matched sedation-and-reversal kit like this so a veterinarian has the sedating agents and their reversal agents prepared together. Your veterinarian determines whether it is appropriate for the procedure and patient.
Medetomidine is an alpha-2 adrenergic agonist; it produces sedation and analgesia. Ketamine is a dissociative anesthetic; it acts on NMDA receptors to produce anesthesia. Butorphanol is an opioid analgesic; it acts on opioid receptors for pain relief and sedation. Midazolam is a benzodiazepine; it provides muscle relaxation and sedation. Atipamezole is an alpha-2 antagonist reversal agent; it reverses the effects of alpha-2 agonists. Naltrexone is an opioid antagonist reversal agent; it reverses the effects of opioids.
This description reflects the general pharmacology of the active ingredients' drug classes; your veterinarian determines whether this approach is appropriate for your animal. Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring. Compounded drugs are not approved by the FDA for safety or effectiveness.
These are potent injectable agents for administration by, or under the direct supervision of, a licensed veterinarian only. The patient must be monitored throughout sedation and recovery. Some components are controlled substances; the included reversal agents are dosed and timed at the veterinarian's direction. Store securely as directed and keep out of reach of children and other animals.
Yes. MKBM™ Kit (Sedation & Reversal) is a compounded kit dispensed only with a prescription and is intended for veterinary use.
It is intended for administration by, or under the direct supervision of, a licensed veterinarian, with the patient monitored throughout sedation and recovery.
Atipamezole and Naltrexone are included so the veterinarian can reverse the effects of the sedating agents when appropriate.
Each agent contributes a different action: Medetomidine is an alpha-2 adrenergic agonist; it produces sedation and analgesia. Ketamine is a dissociative anesthetic; it acts on NMDA receptors to produce anesthesia. Butorphanol is an opioid analgesic; it acts on opioid receptors for pain relief and sedation. Midazolam is a benzodiazepine; it provides muscle relaxation and sedation. Atipamezole is an alpha-2 antagonist reversal agent; it reverses the effects of alpha-2 agonists. Naltrexone is an opioid antagonist reversal agent; it reverses the effects of opioids.
Store securely per the label, keep it out of reach of children and other animals and dispose of components according to your veterinarian's guidance and local regulations.
