Leucovorin Tablet
Leucovorin is a compounded formulation containing Leucovorin, prepared by Mixlab for veterinary use. Available by prescription.
The uses and pharmacology described below reflect the FDA-approved labeling for this active ingredient; your veterinarian determines whether and how they apply to your animal's treatment plan.
Leucovorin calcium, also known as folinic acid, is a reduced form of folic acid utilized in veterinary medicine as a rescue agent or supportive care medication. It is a prescription medication available for use in dogs and cats, requiring professional guidance from a licensed veterinarian. It is frequently considered in the context of oncology for patients receiving high-dose methotrexate or specific chemotherapy protocols.
Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring. Compounded drugs are not approved by the FDA for safety or effectiveness.
At a pharmacological level, it provides a source of folate that bypasses the metabolic block induced by certain medications, providing a method for managing the risk of systemic toxicity. Commonly observed effects are extremely rare, but your veterinarian will monitor for observational signs of localized sensitivity. Owners should monitor for any unusual behavioral changes and contact their veterinarian promptly with any concerns. It is typically evaluated carefully in patients presented with a history of seizures or significant renal impairment.
Yes. Leucovorin is a prescription medication and requires a valid authorization from a licensed veterinarian. Mixlab verifies all professional authorizations before preparing any medication.
Yes. Mixlab specializes in compounding leucovorin into customized strengths and flavored oral formats, such as flavored oral liquids, to support easier administration for your pet.
Veterinarians discuss leucovorin as a rescue agent because it is considered to protect healthy cells from the toxicity of certain chemotherapy medications. This provides a method for managing your pet's comfort during cancer management.
While related to folic acid, leucovorin is a different chemical form that is utilized specifically in a clinical context. Your veterinarian will determine which form is appropriate for your pet's needs.
Your veterinarian will provide guidance on the necessary timing and duration of leucovorin administration. They will monitor your pet's clinical status and blood work to ensure the protocol remains appropriate.
