HydrOXYzine HCl Powder

Rx approval required

We'll contact your veterinarian to review your medication request. If you aren't sure of the correct size and dose, please contact them directly or get in touch with our team.

Select Strength: 500mg/5cc scoop

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Select size: (100 Scoops)

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Also available as a Oral Suspension (Anhydrous)Chew Treat

The hydrochloride salt form of hydroxyzine, used similarly as an antihistamine in veterinary patients to treat allergic dermatitis, itching, and other hypersensitivity reactions. Given by mouth, it provides relief by counteracting histamine in the body and often causes mild sedation, which can help soothe pets suffering from allergy-related discomfort.

Powder medications are meant to be mixed into food or treats, not given on their own (since most pets won’t lick up plain powder). The key is to mix it into something tasty so your pet eats the entire dose.

How to Give It:

Measure the dose using the included scoop or follow the instructions. If you’re unsure how much to give, ask your vet or pharmacist.
Mix it with a small amount of soft food or treat—like wet food, baby food (meat flavor), peanut butter (xylitol-free), yogurt, or cheese. Use just enough to hide the powder so your pet finishes it all in one go.
Stir it well to blend the powder in evenly. Add a splash of water if needed to make it smoother.
Offer it when your pet is a little hungry, and watch to make sure they eat the whole thing.
If your pet refuses, try something else they love next time. For cats, you can also try smearing the paste on their paw to lick off (only if safe and comfortable).
For large animals, mix the powder into a small portion of feed with water or molasses, then follow with the rest of their food once they’ve eaten the medicated part.
Store the powder in a cool, dry place with the lid closed tightly.

Never give powder straight into your pet’s mouth—it can be dangerous if inhaled.

Mixlab is a licensed veterinary pharmacy dispensing both compounded and commercial medications, operating under the oversight of licensed pharmacists and in compliance with applicable state and federal pharmacy regulations. Compounded medications are prepared in compliance with USP standards and under PCAB-accredited practices. All medications dispensed by Mixlab require a valid prescription from a licensed veterinarian.