Sign up
Hydrocodone/Homatropine Oral Solution

Hydrocodone/Homatropine Oral Solution

Rx approval required
We'll contact your veterinarian to review your medication request. If you aren't sure of the correct size and dose, please contact them directly or get in touch with our team.
Select Strength: 5mg/1.5mg/5mL
Select size: 60 mL
Sign up
Are you a prescriber?
Login to our prescriber platform, eMix, to prescribe with Mixlab.
Also available as a Tablet

Hydrocodone/Homatropine is a compounded formulation containing Hydrocodone, Homatropine, prepared by Mixlab for veterinary use. Available by prescription.

How to Give Oral Solution

Oral solutions are liquid medications that you give by mouth. In a solution, the medication is completely dissolved in the liquid, so it usually looks clear or evenly colored. Here's how to give it:

  1. Shake well each time to mix the medication (5-10 seconds).
  2. Measure the dose using the syringe/dropper provided or one recommended by your vet. Insert the top of the oral syringe into the bottle adapter. Turn the bottle upside down and pull the plunger until the medicine reaches the volume required
  3. Hold your pet steady: a towel or helper can assist with squirmy pets.
  4. Administer the dose slowly into the side of the mouth. Allow small pauses if needed for swallowing.
  5. Raise the head slightly to help the medication go down and clean any spills with a little water or tissue.
  6. Praise your pet and offer a treat or water (unless advised against feeding right after).
  7. Clean the syringe with water immediately after use. Store the bottle as directed, out of sunlight.
  8. Consistency is key: Shake each time, measure accurately, and contact your vet if any issues arise.

This compounded formulation combines hydrocodone, an opioid, with homatropine, an anticholinergic — two different drug classes. In compounding practice, clinicians may consider a combination like this for a multi-targeted approach. Your veterinarian determines whether it is appropriate based on your animal's diagnostic findings.

This description reflects the general pharmacology of the active ingredient's drug class; your veterinarian determines whether this approach is appropriate for your animal.

Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring. Compounded drugs are not approved by the FDA for safety or effectiveness.

At a pharmacological level, hydrocodone manages the cough center in the brain, while homatropine manage localized respiratory secretions and digestive comfort. Commonly observed effects include behavioral shifts such as sedation, lethargy and localized changes like dry mouth or constipation. Because it influences the central nervous system, your veterinarian will monitor for observational signs of sensitivity. Owners should monitor for significant changes in activity levels and contact their veterinarian promptly with any concerns regarding the patient's response to the medication.

Do I need a prescription?

Yes. Hydrocodone and homatropine is a prescription medication and a controlled substance. Mixlab verifies all legal requirements before any medication is prepared.

Can this be compounded for my pet?

Yes. Mixlab specializes in compounding the combination of hydrocodone and homatropine into customized flavored formats, such as oral liquids, to support easier administration for your pet.

How does this help with my dog's cough?

Veterinarians discuss this combination because it acts on the brain to manage the frequency of coughing while also managing localized airway secretions. This provides a method for managing comfort in pets with chronic lung challenges.

Are there side effects I should watch for?

Commonly observed effects include drowsiness, dry mouth and constipation. Your veterinarian will provide guidance on monitoring your pet's energy and appetite during the course of management.

Is this safe for all dogs?

This combination is typically used with caution in dogs with certain heart or lung conditions. Your veterinarian will determine if this management approach is appropriate for your individual pet’s health status.

Mixlab is a licensed veterinary pharmacy dispensing both compounded and commercial medications, operating under the oversight of licensed pharmacists and in compliance with applicable state and federal pharmacy regulations. Compounded medications are prepared in compliance with USP standards and under PCAB-accredited practices. All medications dispensed by Mixlab require a valid prescription from a licensed veterinarian.
You may also like
We use cookies and similar technologies, including from analytics providers, to operate our site and understand how it's used. We do not sell your data or allow third-party advertising. See our Privacy Policy for details. Click "Reject" to decline non-essential cookies.