Furosemide/Spironolactone Oral Suspension (Anhydrous)
Furosemide/Spironolactone is a compounded dual-action diuretic medication prescribed for dogs and cats to manage fluid retention. It combines a loop diuretic to promote rapid fluid clearance with a potassium-sparing diuretic to block aldosterone, reducing the workload on the heart while helping to prevent excessive potassium loss. This combination is utilized in the daily management of congestive heart failure and related fluid accumulation in the chest or abdomen.
How to Give Anhydrous Oral Suspension
Oral Suspension (Anhydrous) is a liquid medication that does not contain water in its base. This might be an oil-based or other special base to help stabilize the medicine. It will look like a regular liquid medication, but often needs a good shake because the drug can settle. Here's how to give it:
- Shake well each time to mix the medication (5-10 seconds).
- Measure the dose using the syringe/dropper provided or one recommended by your vet. Insert the top of the oral syringe into the bottle adapter. Turn the bottle upside down and pull the plunger until the medicine reaches the volume required
- Hold your pet steady: a towel or helper can assist with squirmy pets.
- Administer the dose slowly into the side of the mouth. Allow small pauses if needed for swallowing.
- Raise the head slightly to help the medication go down and clean any spills with a little water or tissue.
- Praise your pet and offer a treat or water (unless advised against feeding right after).
- Clean the syringe with water immediately after use. Store the bottle as directed, out of sunlight.
- Consistency is key: Shake each time, measure accurately, and contact your vet if any issues arise.
This compounded formulation combines active ingredients from different drug classes: furosemide, a loop diuretic and spironolactone, an aldosterone-antagonist (potassium-sparing) diuretic. In compounding practice, clinicians may consider a combination like this to consolidate more than one medication into a single administration. Your veterinarian determines whether it is appropriate based on your animal's diagnostic findings.
Furosemide promotes the excretion of sodium, chloride and water at the loop of Henle; spironolactone blocks the effects of aldosterone, influencing sodium and potassium balance.
This description reflects the general pharmacology of the active ingredient's drug class; your veterinarian determines whether this approach is appropriate for your animal.
Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring. Compounded drugs are not approved by the FDA for safety or effectiveness.
Because this preparation combines two diuretics with different effects on electrolytes, your veterinarian will individualize it and monitor kidney values and electrolytes, especially potassium. Ensure access to fresh water and report reduced appetite, weakness or changes in urination.
Yes. This is a prescription product and can only be dispensed by a licensed pharmacy after a valid prescription is received from a licensed veterinarian. Mixlab verifies every prescription before dispensing.
Yes. Mixlab can compound this combination in the strength and format your veterinarian specifies for your animal.
Each active contributes a different mechanism. Your veterinarian determines whether a combined preparation is appropriate for your animal's situation.
Your veterinarian will individualize the preparation and may recommend periodic monitoring to keep the plan appropriate for your pet.
