Fenbendazole/Praziquantel Oral Suspension (Anhydrous)
Fenbendazole/Praziquantel is a compounded formulation containing Fenbendazole, Praziquantel, prepared by Mixlab for veterinary use. Available by prescription.
How to Give Anhydrous Oral Suspension
Oral Suspension (Anhydrous) is a liquid medication that does not contain water in its base. This might be an oil-based or other special base to help stabilize the medicine. It will look like a regular liquid medication, but often needs a good shake because the drug can settle. Here's how to give it:
- Shake well each time to mix the medication (5-10 seconds).
- Measure the dose using the syringe/dropper provided or one recommended by your vet. Insert the top of the oral syringe into the bottle adapter. Turn the bottle upside down and pull the plunger until the medicine reaches the volume required
- Hold your pet steady: a towel or helper can assist with squirmy pets.
- Administer the dose slowly into the side of the mouth. Allow small pauses if needed for swallowing.
- Raise the head slightly to help the medication go down and clean any spills with a little water or tissue.
- Praise your pet and offer a treat or water (unless advised against feeding right after).
- Clean the syringe with water immediately after use. Store the bottle as directed, out of sunlight.
- Consistency is key: Shake each time, measure accurately, and contact your vet if any issues arise.
This compounded formulation combines fenbendazole, an anthelmintic (dewormer), with praziquantel, an anthelmintic (dewormer) — two different drug classes. In compounding practice, clinicians may consider a combination like this for a multi-targeted approach. Your veterinarian determines whether it is appropriate based on your animal's diagnostic findings.
At a pharmacological level, the components of this formulation act through independent mechanisms to disrupt parasitic stability. Fenbendazole acts by binding to tubulin, a structural protein essential for the formation of microtubules within the parasite. This inhibition disrupts the parasite’s ability to transport glucose and maintain its energy metabolism, eventually leading to its elimination from the host. Praziquantel acts specifically on flatworms (tapeworms) by increasing the permeability of the parasite’s cell membranes to calcium ions. This shift induces rapid, spastic contraction and vacuolization of the parasite's protective integument, causing the tapeworms to detach from the intestinal wall and be digested or expelled. Your veterinarian will determine if this combination is appropriate based on the species, weight and results of diagnostic testing.
This description reflects the general pharmacology of the active ingredient's drug class; your veterinarian determines whether this approach is appropriate for your animal.
Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring. Compounded drugs are not approved by the FDA for safety or effectiveness.
Commonly observed effects of fenbendazole/praziquantel administration include mild gastrointestinal changes such as loose stools, vomiting or a temporary decrease in appetite. In animals with significant parasitic burdens, owners may observe a transient physiological response as the body reacts to the dying parasites, which is often discussed by veterinarians as a normal part of the process. If you observe significant stumbling, persistent diarrhea or signs of an acute allergic reaction, contact your veterinarian promptly.
This medication is typically used with caution in severely debilitated animals, though it generally possesses a favorable safety profile across most patient categories. It is also carefully evaluated in breeding, pregnant or lactating animals, as the safety profile for developing offspring is a point of professional consideration. Before starting a protocol involving fenbendazole/praziquantel, ensure your veterinarian has a complete history of all other supplements and prescriptions your pet is receiving. Your veterinarian is the right person to design a comprehensive monitoring plan and provide guidance on environmental management to ensure the approach remains suitable for your pet's individual health status.
Yes. Fenbendazole/praziquantel is a combination of prescription medications and can only be dispensed by a licensed pharmacy upon receipt of a valid authorization from a licensed veterinarian. Mixlab verifies all authorizations before any medication is prepared or shipped to your stable or home.
Yes. While individual components may be available in various commercial formats, Mixlab can compound this specific combination into specialized strengths or alternative flavored dosage forms—such as oral liquids, chews or capsules—if your veterinarian determines a customized preparation better suits your animal’s needs. The decision between a commercial and compounded product rests with the prescribing veterinarian.
Veterinarians may consider combining these ingredients so the preparation can act through more than one mechanism at once — here, it brings together complementary actions in one preparation. Your veterinarian determines whether this multi-targeted approach is appropriate for your pet.
Owners should monitor for mild digestive upset, such as a decrease in appetite or loose stools, which are the most commonly observed effects. If your pet has a high number of parasites, you may also observe them in the stool as the medication begins to act and you should contact your veterinarian with any concerns about your pet’s energy levels.
