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FamOTIDINE/Metoclopramide Oral Suspension (Anhydrous)

FamOTIDINE/Metoclopramide Oral Suspension (Anhydrous)

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Famotidine and Metoclopramide are used under veterinary supervision to treat severe gastrointestinal issues like persistent vomiting and gastric reflux. The two drugs work together to address both excess stomach acid and poor stomach motility.

How to Give Anhydrous Oral Suspension

Oral Suspension (Anhydrous) is a liquid medication that does not contain water in its base. This might be an oil-based or other special base to help stabilize the medicine. It will look like a regular liquid medication, but often needs a good shake because the drug can settle. Here's how to give it:

  1. Shake well each time to mix the medication (5-10 seconds).
  2. Measure the dose using the syringe/dropper provided or one recommended by your vet. Insert the top of the oral syringe into the bottle adapter. Turn the bottle upside down and pull the plunger until the medicine reaches the volume required
  3. Hold your pet steady: a towel or helper can assist with squirmy pets.
  4. Administer the dose slowly into the side of the mouth. Allow small pauses if needed for swallowing.
  5. Raise the head slightly to help the medication go down and clean any spills with a little water or tissue.
  6. Praise your pet and offer a treat or water (unless advised against feeding right after).
  7. Clean the syringe with water immediately after use. Store the bottle as directed, out of sunlight.
  8. Consistency is key: Shake each time, measure accurately, and contact your vet if any issues arise.

This compounded formulation combines famotidine, an H2-receptor antagonist, with metoclopramide, a prokinetic and antiemetic — two different drug classes. In compounding practice, clinicians may consider a combination like this for a multi-targeted approach. Your veterinarian determines whether it is appropriate based on your animal's diagnostic findings.

This description reflects the general pharmacology of the active ingredient's drug class; your veterinarian determines whether this approach is appropriate for your animal.

Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring. Compounded drugs are not approved by the FDA for safety or effectiveness.

At a pharmacological level, famotidine manages gastric acid production while metoclopramide manages gastrointestinal transit by sensitizing tissues to acetylcholine. Commonly observed effects include behavioral shifts such as restlessness, temporary lethargy or localized digestive changes like diarrhea. It is typically used with caution in patients with a history of seizures or known gastrointestinal obstruction. Owners should monitor for significant behavioral changes or coordination shifts and contact their veterinarian promptly with concerns.

Do I need a prescription for this combination?

Yes. This combination of famotidine and metoclopramide is a prescription medication and requires a valid authorization from a licensed veterinarian. Mixlab verifies all legal authorizations before Preparing any medication.

Can this combination be compounded for my pet?

Yes. Mixlab specializes in compounding famotidine and metoclopramide into customized strengths and flavored oral formats, such as flavored liquids or treats, to support easier administration. The decision rests with your prescribing veterinarian.

Why are these two medications combined?

Veterinarians discuss this combination when a pet requires management for both stomach acid and delayed gastric emptying. By managing both pathways, it provides a method for addressing comprehensive digestive discomfort.

What should I watch for after a dose?

You should monitor for observational signs like improved appetite or reduced lip smacking. If you notice your pet appearing unusually agitated or restless, contact your veterinarian for a clinical review of the management plan.

Can I give this to my pet with a blocked stomach?

Metoclopramide is typically avoided in patients where a mechanical obstruction is suspected. Your veterinarian will perform a professional examination to ensure this management approach is appropriate for your pet’s specific condition.

Mixlab is a licensed veterinary pharmacy dispensing both compounded and commercial medications, operating under the oversight of licensed pharmacists and in compliance with applicable state and federal pharmacy regulations. Compounded medications are prepared in compliance with USP standards and under PCAB-accredited practices. All medications dispensed by Mixlab require a valid prescription from a licensed veterinarian.
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