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Enalapril Maleate/Furosemide Transdermal Pen (3mL)

Enalapril Maleate/Furosemide Transdermal Pen (3mL)

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Select Strength: 2.5/25mg/0.1ml
Select count: 1 ea
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Enalapril Maleate/Furosemide is a compounded formulation containing Enalapril Maleate, Furosemide, prepared by Mixlab for veterinary use. Available by prescription.

A transdermal pen is a simple way to give your pet medicine through their skin—usually used for cats by applying gel to the inside of their ear.

Step-by-Step:

  1. Get the pen ready – Twist the pen to dispense a small amount of gel. If it’s your first time, you will need to “prime” it first (the gel should be flush with the edge of the tip)
  2. Wear gloves – Always use a disposable glove or finger cot so the medication doesn’t absorb into your skin.
  3. Twist to dose – Follow the pen’s directions (like two full twists) to get the right amount of gel out. Always click in a clockwise direction, clicking counter-clockwise will stop you
  4. Pick the spot – Apply to a hairless area, usually the inside of your cat’s ear. Make sure the area is clean and dry.
  5. Apply the gel – Dab the gel directly with the pen or use your gloved finger to rub it in gently. Avoid the ear canal.
  6. Let it dry – It usually dries in a minute or two. Try to keep your pet from rubbing it off.
  7. Recap the pen – This keeps the medication fresh.
  8. Wash your hands – Even if you wore gloves, wash thoroughly after.
  9. Reward your pet – A treat helps make it a stress-free routine!
  10. Store properly – Keep at room temp, away from sunlight. Track doses so you know when it’s time to refill.

Important: Only apply where your vet has directed—usually hairless areas. Never apply over fur or broken skin. Keep other pets from licking the area until it’s dry.

This compounded formulation combines enalapril, an ACE inhibitor, with furosemide, a loop diuretic — two different drug classes. In compounding practice, clinicians may consider a combination like this for a multi-targeted approach. Your veterinarian determines whether it is appropriate based on your animal's diagnostic findings.

This description reflects the general pharmacology of the active ingredient's drug class; your veterinarian determines whether this approach is appropriate for your animal.

Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring. Compounded drugs are not approved by the FDA for safety or effectiveness.

Commonly observed effects include behavioral shifts such as increased thirst and urination (polyuria/polydipsia) and localized digestive changes like a temporary decrease in appetite. Because both ingredients influence renal and electrolyte status, your veterinarian will monitor for observational signs of dehydration or weakness. It is typically used with caution in patients with pre-existing renal impairment or electrolyte imbalances. Owners should monitor their pet for any unusual lethargy and contact their veterinarian promptly with concerns.

Do I need a prescription for this combination?

Yes. This combination of enalapril and furosemide is a prescription medication and requires a valid authorization from a licensed veterinarian. Mixlab verifies all requirements before dispensing.

Can this be compounded for my pet?

Yes. Mixlab specializes in compounding enalapril and furosemide into customized flavored oral formats to suit your pet's needs. The decision between a commercial and compounded product rests with the prescribing veterinarian.

Why are these two medications used together?

Veterinarians discuss this combination because it manages both the fluid buildup in the body and the pressure in the blood vessels. This provides a method for managing the heart's workload through complementary mechanisms.

Will my pet pee more on this medication?

Increased urination is a commonly observed effect of the diuretic component, furosemide. Your veterinarian will provide guidance on managing your pet's hydration and access to outdoor areas during the course of management.

What monitoring does my pet need?

Your veterinarian will recommend periodic blood tests to monitor kidney values and electrolyte levels. This monitoring ensures the management approach remains appropriate for your pet.

Mixlab is a licensed veterinary pharmacy dispensing both compounded and commercial medications, operating under the oversight of licensed pharmacists and in compliance with applicable state and federal pharmacy regulations. Compounded medications are prepared in compliance with USP standards and under PCAB-accredited practices. All medications dispensed by Mixlab require a valid prescription from a licensed veterinarian.
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