Doxycycline (as Hyclate)/KETOconazole/Triamcinolone clEARmix Lanolin Otic (3mL Syringe)
Doxycycline (as hyclate)/Ketoconazole/Triamcinolone Lanolin Otic is a veterinary ear medication used to treat mixed ear infections in dogs and cats, particularly those involving bacteria and yeast. It combines an antibiotic (doxycycline) to fight bacteria, an antifungal (ketoconazole) to target yeast such as Malassezia, and a corticosteroid (triamcinolone) to reduce inflammation, redness, itching, and discomfort. The lanolin base allows for once weekly dosing and helps soothe and protect the irritated ear canal during healing.
How to Use clEARmix Lanolin Otic (Ear Medication)
This is a thick ear ointment used to treat ear infections. It comes in a pre-filled syringe with a soft tip, making it easier to apply and designed to stay in your pet’s ear longer.
Step-by-Step: 1. Warm the syringe – If it’s cold, hold it in your hands for a minute to soften the ointment. Do not microwave. 2. Position your pet – Have them sit in a comfy spot. You may need someone to gently help hold them. Lift their ear flap straight up. 3. Clean the ear (if needed) – Only if your vet told you to. Use a vet-approved ear cleaner and cotton ball—never a Q-tip deep in the ear. Let the ear dry. 4. Apply the medication – Remove the cap, then gently insert just the tip of the syringe into the ear opening. Don’t push in deep. 5. Dispense slowly – Press the plunger gently to apply the full dose or the amount your vet prescribed. 6. Massage the ear – Rub the base of the ear for about 30 seconds to help the medication spread. 7. Let them shake – It’s normal! Wipe off any excess with a tissue or cloth. 8. Reward your pet – Give them praise and maybe a treat to make it a positive experience. 9. Store the rest – If there’s more medication left, recap the syringe and store at room temp. Wash your hands after use.
This compounded formulation combines active ingredients from different drug classes: doxycycline, a tetracycline antibiotic; ketoconazole, an azole antifungal; and triamcinolone, a corticosteroid. In compounding practice, clinicians may consider a multi-ingredient preparation like this to address more than one aspect of a patient's physiology at once. Your veterinarian determines whether it is appropriate based on your animal's diagnostic findings.
This description reflects the general pharmacology of the active ingredient's drug class; your veterinarian determines whether this approach is appropriate for your animal.
Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring. Compounded drugs are not approved by the FDA for safety or effectiveness.
Commonly observed effects include localized changes such as mild redness or temporary irritation. Because the formulation contains a corticosteroid, your veterinarian will monitor for observational signs of systemic influence including shifts in thirst or urination. Ensuring the tympanic membrane is intact is a high-priority clinical safety step. Owners should monitor their pet for behavioral shifts like a head tilt or sudden hearing changes and contact their veterinarian promptly with concerns.
Yes. This medication requires a valid prescription from a licensed veterinarian before it can be dispensed. Mixlab verifies authorization before any medication is prepared or shipped to your home.
Yes. Mixlab specializes in compounding this combination into customized otic formats to suit the specific needs of your pet’s ears. The decision between a commercial and compounded product rests with the prescribing veterinarian.
Veterinarians may consider combining these ingredients so the preparation can act through more than one mechanism at once — here, it brings together antibacterial, antifungal and anti-inflammatory actions in one preparation. Your veterinarian determines whether this multi-targeted approach is appropriate for your pet.
You should monitor for observational signs such as reduced scratching, a decrease in ear odor or a reduction in redness. Your veterinarian will provide a specific monitoring schedule based on your pet's needs.
Your veterinarian will determine the necessary duration of use based on your pet's clinical response. They will monitor for any signs that the management approach should be adjusted.
