
Diltiazem HCl ER is an FDA-approved commercial extended-release product, dispensed by Mixlab for veterinary use in cats and dogs. Available by prescription.
Use as directed by your veterinarian.
The uses and pharmacology described below reflect the FDA-approved labeling for this active ingredient; your veterinarian determines whether and how they apply to your animal's treatment plan.
Diltiazem is a calcium channel blocker that relaxes blood vessels and slows certain electrical activity in the heart; the extended-release formulation is intended for once-daily dosing. On the FDA-approved human label, it is indicated for hypertension and certain heart rhythm conditions.
In veterinary medicine, extended-release diltiazem has been studied for once-daily use in cats, most often to help manage hypertrophic cardiomyopathy, and is used in dogs for certain arrhythmias or hypertension. This information is not a substitute for veterinary diagnosis, prescribing, or monitoring.
Extended-release products are not interchangeable between brands or formulations — do not switch products or crush/split this medication without your veterinarian's specific direction, since absorption can vary between different extended-release diltiazem formulations. Commonly reported effects include decreased appetite, lethargy, and low blood pressure; slow heart rate has also been reported. Your veterinarian will likely recommend periodic monitoring, which may include blood pressure checks or echocardiograms.
Yes. Diltiazem is available only by prescription from a licensed veterinarian.
The active ingredient has an FDA-approved human label. Mixlab dispenses the commercial extended-release product under a licensed veterinarian's prescription for use in your pet.
The extended-release form is used to help manage hypertrophic cardiomyopathy in cats and certain arrhythmias or hypertension in dogs, often for once-daily dosing convenience. Your veterinarian determines the appropriate use for your pet.
Contact Mixlab to discuss your patient's specific needs — compounding options are evaluated case by case.




