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Diclofenac Ophthalmic Solution

Diclofenac Ophthalmic Solution

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Select Strength: 0.10%
Select size: 5mL bottle
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Diclofenac is a compounded formulation containing Diclofenac, prepared by Mixlab for veterinary use. Available by prescription.

How to Give Your Pet Eye Drops (Ophthalmic Solutions)

Eye drops are liquid medications used to treat your pet’s eye conditions. They’re clear, gentle, and effective with the right technique. With a bit of practice, you and your pet will get the hang of it!

Step-by-Step Guide:

  1. Wash Your Hands: Start clean to avoid germs.
  2. Get Your Pet Comfortable: Sit your dog or wrap your cat in a towel (“kitty burrito”) to keep them still. A helper can gently steady the head.
  3. Clean the Eye (if needed): Use a damp cotton ball or gauze to gently wipe any discharge.
  4. Position the Bottle: Hold the bottle in your dominant hand. Use the other hand to tilt your pet’s head and gently pull down the lower eyelid to create a small pocket.
  5. Apply the Drops: Hold the bottle close (but not touching the eye) and squeeze in the prescribed number of drops. Aim for the center of the eye or into the pocket.
  6. Let Your Pet Blink: Blinking helps spread the medication. Gently blot away excess drops.
  7. Repeat for the Other Eye (if needed): Use the same care and steps.
  8. Prevent Rubbing: Hold your pet briefly to stop rubbing. Offer gentle praise or a treat!
  9. Multiple Eye Meds?: Wait 5–10 minutes between different meds. Use watery drops before thicker ointments, unless told otherwise.
  10. Store Properly: Recap the bottle and store it as directed (usually at room temp).

The uses and pharmacology described below reflect the FDA-approved labeling for this active ingredient; your veterinarian determines whether and how they apply to your animal's treatment plan.

Veterinarians most commonly consider diclofenac sodium for patients presented with ocular challenges, such as uveitis or localized inflammation following ophthalmic surgical procedures. It is frequently a point of discussion when managing the physiological environment of the eye during the recovery period after cataract surgery. The decision to select this specific NSAID is often based on a veterinarian's objective to address inflammatory mediators within the anterior segment of the eye without the systemic influence sometimes associated with oral medications.

At a pharmacological level, diclofenac acts by inhibiting the cyclooxygenase (COX) enzyme system, which is a component of the inflammatory cascade. This mechanism manages the production of prostaglandins—chemical messengers that signal inflammation and contribute to localized discomfort. By delivering the medication directly to the ocular surface, the formulation provide a method for managing the concentrations of these mediators within the aqueous humor and surrounding tissues. Your veterinarian will determine the clinical appropriateness of diclofenac based on a professional ophthalmic examination, which may include tonometry or fluorescein staining to assess the health of the corneal surface.

Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring. Compounded drugs are not approved by the FDA for safety or effectiveness.

Commonly observed effects following the administration of diclofenac eye drops include localized changes at the application site, such as mild redness, increased tearing or temporary stinging. Some pets may exhibit observational signs of squinting or head rubbing shortly after the drops are applied. While diclofenac is used topically, minimal systemic absorption is possible; your veterinarian will monitor for signs such as localized digestive changes or changes in thirst, particularly in patients with pre-existing health challenges. Owners should monitor their pet for any unusual behavioral shifts or persistent ocular discharge and contact their veterinarian promptly with any concerns regarding the patient's response.

This medication is typically used with extra caution or avoided in patients with known corneal ulcers, as medications in the NSAID class can influence the healing process of the corneal epithelium. It is also carefully evaluated in pets with a history of bleeding disorders or those presented with pre-existing renal or hepatic impairment. Significant interactions can occur if diclofenac is administered concurrently with other topical medications, such as corticosteroids or specific glaucoma management protocols. Your veterinarian is the right person to provide guidance on the necessary frequency of use and the most appropriate monitoring schedule to ensure the management approach remains suitable for your pet's ocular recovery and long-term health.

Do I need a prescription to get diclofenac for my pet?

Yes. Diclofenac is a prescription ophthalmic medication and can only be dispensed by a licensed pharmacy upon receipt of a valid authorization from a licensed veterinarian. Mixlab verifies all legal authorizations before any medication is prepared or shipped to your home.

Can diclofenac be compounded for my pet?

Yes. While diclofenac is available in commercial ophthalmic solution formats, Mixlab specializes in compounding the active ingredient into customized strengths or specific sterile vehicles when a veterinarian determines that a customized preparation better suits an individual patient's needs. The decision between a commercial and compounded product rests with the prescribing veterinarian.

Why is diclofenac used for my pet's eyes?

Veterinarians discuss diclofenac for the eyes because it manages the production of prostaglandins that cause localized inflammation and swelling. This provides a method for managing the physiological environment of the eye during chronic challenges or after surgery.

Can I use these drops if my pet has an eye scratch?

Veterinarians typically perform a professional exam to check for a corneal ulcer or "scratch" before authorizing diclofenac, as NSAIDs can influence the eye's ability to heal. If an ulcer is suspected, your veterinarian will determine the most appropriate alternative management plan for your pet.

What safety precautions should I take when applying this medication?

Your veterinarian will likely recommend washing your hands thoroughly before and after application and avoiding contact between the dropper tip and your pet's eye or skin. This provides a method for preventing contamination of the sterile solution and ensuring the management course remains suitable.

Mixlab is a licensed veterinary pharmacy dispensing both compounded and commercial medications, operating under the oversight of licensed pharmacists and in compliance with applicable state and federal pharmacy regulations. Compounded medications are prepared in compliance with USP standards and under PCAB-accredited practices. All medications dispensed by Mixlab require a valid prescription from a licensed veterinarian.
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