
per Tablet S-Adenosylmethionine 90 mg, Silybin A+B 9 mg
Dogs up to 12lbs - 1 tablet daily; Over 12lbs - 2 tablets daily
Denamarin is a supplement combining S-adenosylmethionine (SAMe) and silybin (a milk thistle-derived compound, provided as a silybin-phosphatidylcholine complex), ingredients studied in the context of liver cell health.
SAMe is a naturally occurring molecule involved in several biochemical pathways in the liver, including the production of glutathione, one of the body's antioxidants. Silybin is a compound derived from milk thistle that is studied for its antioxidant properties at the cellular level. As a multi-ingredient nutraceutical, this combination is not reviewed or approved by the FDA in the way a drug would be; your veterinarian determines whether a liver-support supplement is appropriate for your animal.
This description reflects general information about the supplement's ingredients; your veterinarian determines whether this product is appropriate for your animal.
This information describes a dietary supplement. Supplements are not evaluated by the FDA for safety or effectiveness and are not intended to diagnose, treat, cure, or prevent any disease. Consult your veterinarian before use.
This supplement is generally well tolerated in dogs and cats; mild digestive changes such as decreased appetite, vomiting, or soft stool are occasionally reported, particularly when starting the supplement. SAMe tablets are enteric-coated in most formulations and should not be split or crushed unless your veterinarian specifically directs otherwise, as this can affect absorption. Contact your veterinarian if you notice persistent vomiting, diarrhea, or a lack of appetite. As with any supplement, keep your veterinarian informed of everything your dog receives so they can watch for potential interactions and confirm the product remains appropriate.
No. This is a dietary supplement and does not require a prescription. It's available for purchase directly through Mixlab.
SAMe absorption can be affected by food; many labels recommend giving it on an empty stomach. Follow the label directions and your veterinarian's specific instructions for your animal.
Let your veterinarian know about all other medications and supplements your animal is taking so they can advise on how this fits into your animal's overall plan, particularly around timing with other oral medications.
Duration varies by animal and by what your veterinarian is monitoring. Your veterinarian will advise on an appropriate length of use and any recommended bloodwork or rechecks.