Credelio Chewable Tablet
Credelio is an FDA-approved preparation containing Credelio, for veterinary use. Available by prescription.
Credelio® is a commercial brand of lotilaner, a systemic insecticide and acaricide utilized in veterinary medicine for the management of flea and tick infestations. This prescription medication is formulated as a flavored chewable tablet for use in dogs and cats, frequently considered by veterinarians for year-round parasite prevention. At a pharmacological level, lotilaner acts as an inhibitor of gamma-aminobutyric acid (GABA)-gated chloride channels in the nervous system of insects and acari. This inhibition manages the flow of chloride ions, leading to uncontrolled neuromuscular activity and disruption of the parasite's nervous system function. Credelio® is characterized by its ability to manage active flea populations shortly after administration and provide a method for managing multiple tick species for a full month. Your veterinarian will determine the appropriateness of Credelio® based on your pet’s weight, age and exposure risk.
The actions described here reflect the product's FDA-approved labeling; your veterinarian determines the appropriate use for your animal.
Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring.
Commonly observed effects following the administration of Credelio® include localized digestive changes such as vomiting, diarrhea or a temporary decrease in appetite. Some pets may exhibit behavioral shifts including lethargy or restlessness. While lotilaner belongs to the isoxazoline class, which is associated with potential neurological effects, your veterinarian will weigh this factor based on your pet's health history. Owners should monitor their pet for any unusual signs of tremors, loss of coordination or seizures and contact their veterinarian promptly with any concerns. This medication is typically used with extra caution in pets with a history of seizures or neurological disorders. It is also carefully evaluated in breeding, pregnant or lactating animals. Before starting a protocol, ensure your veterinarian has a complete history of all other medications and parasite preventatives your pet is receiving. Your veterinarian is the right person to provide guidance on the necessary frequency of use to ensure the management approach remains suitable for your pet's needs.
Yes. Credelio is a prescription parasite medication and can only be dispensed by a licensed pharmacy upon receipt of a valid authorization from a licensed veterinarian. Mixlab ensures all prescription requirements are met before any medication is prepared or shipped.
Credelio is a proprietary commercial flavored chewable tablet. While Mixlab specializes in compounding many customized medications, Credelio is typically dispensed in its original commercial format. Your veterinarian can discuss alternative parasite management options if your pet has specific administration needs.
Veterinarians typically recommend giving Credelio once every month to ensure continuous management of fleas and ticks. Your veterinarian will provide guidance on the proper schedule based on your pet's weight and local parasite risks.
Yes. Veterinarians recommend administering Credelio with a meal or within 30 minutes of feeding to ensure the medication is absorbed and commonly considered. Giving the chewable with food also may be part of a management approach for the risk of localized stomach upset.
