Codeine Phosphate Capsule
Codeine Phosphate is a compounded formulation containing Codeine Phosphate, prepared by Mixlab for veterinary use. Available by prescription.
Use as directed by your veterinarian.
The uses and pharmacology described below reflect the FDA-approved labeling for this active ingredient; your veterinarian determines whether and how they apply to your animal's treatment plan.
Codeine phosphate is an opioid agonist utilized in veterinary medicine primarily for the management of cough and certain types of discomfort. It is a prescription medication available for use in dogs and cats, frequently considered by veterinarians when a centrally acting antitussive (cough suppressant) is a clinical objective. At a pharmacological level, codeine acts by binding to mu-opioid receptors in the central nervous system. This binding manages the excitability of the cough center in the medulla, providing a method for addressing the frequency and intensity of a non-productive cough. It also influences pain pathways, though in veterinary medicine, it is often discussed as part of a multi-modal management plan rather than as a primary analgesic. Your veterinarian will determine the clinical appropriateness of codeine phosphate based on your pet's clinical signs and the nature of their respiratory or comfort needs.
Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring. Compounded drugs are not approved by the FDA for safety or effectiveness.
Commonly observed effects following the administration of codeine include sedation, temporary coordination shifts or localized digestive changes such as constipation and nausea. Some animals may exhibit behavioral shifts including lethargy or, occasionally, paradoxical excitement. Because opioids can influence respiratory drive, owners should monitor their pet's breathing patterns closely and contact their veterinarian promptly with any concerns. This medication is typically used with extra caution or avoided in patients with known severe respiratory disease, head trauma or certain types of abdominal conditions. It is also carefully evaluated in pets with pre-existing hepatic or renal impairment, as these organs are involved in the metabolism and excretion of the medication. Significant interactions can occur if codeine is administered concurrently with other central nervous system depressants or specific medications used for behavioral management. Your veterinarian is the right person to provide guidance on the necessary duration of use and the proper administration schedule to ensure the management approach remains suitable for your pet's individual profile.
Yes. Codeine phosphate is a prescription medication and a controlled substance that can only be dispensed by a licensed pharmacy upon receipt of a valid authorization from a licensed veterinarian. Mixlab ensures all legal and prescription requirements are met before dispensing this medication.
Yes. While codeine is available in commercial tablet and liquid formats, Mixlab specializes in compounding the active ingredient into customized strengths and flavored dosage forms—such as flavored oral liquids—to suit the specific needs of dogs and cats. The decision rests with the prescribing veterinarian.
Veterinarians discuss codeine for cough because it acts directly on the area of the brain that triggers the coughing reflex. By managing this reflex, the medication provides a method for addressing persistent, non-productive coughing that may be causing your pet distress.
Constipation is a commonly observed effect of opioid medications like codeine. Your veterinarian will provide guidance on monitoring your pet's bowel habits and may suggest management adjustments if you notice significant shifts in their digestion.
