
Clarithromycin is a compounded formulation containing Clarithromycin, prepared by Mixlab for veterinary use. Available by prescription.
The uses and pharmacology described below reflect the FDA-approved labeling for this active ingredient; your veterinarian determines whether and how they apply to your animal's treatment plan.
Clarithromycin is a macrolide antibiotic utilized in veterinary medicine for the management of various bacterial and mycobacterial challenges. It is a prescription medication available for use in dogs, cats and horses, particularly when veterinarians seek to address susceptible gram-positive and certain specialized intracellular organisms. Veterinarians most commonly consider clarithromycin for patients presented with respiratory challenges, skin infections or localized tissue concerns. In equine medicine, it is frequently a point of discussion for the management of infections caused by Rhodococcus equi in foals, often in combination with other prescriptions. By targeting the protein production centers of susceptible bacteria, your veterinarian can manage the progression of the infection within the affected organ system.
Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring. Compounded drugs are not approved by the FDA for safety or effectiveness.
Commonly observed effects following the administration of clarithromycin include localized digestive changes such as vomiting, diarrhea or a temporary decrease in appetite. Some animals may exhibit behavioral shifts including lethargy. In foals, a high-priority clinical consideration is the risk of hyperthermia (overheating) or severe respiratory distress when using this class of medication; your veterinarian will provide specific monitoring instructions for pets in this category. Owners should monitor their pet for any unusual changes in breathing or energy levels and contact their veterinarian promptly with any concerns. This medication is typically used with extra caution or avoided in patients with known severe hepatic impairment, as the liver is a primary site for the metabolism of macrolides. It is also carefully evaluated in pets with pre-existing cardiac arrhythmias. Significant interactions can occur if clarithromycin is administered concurrently with certain medications that inhibit liver enzymes or those that influence heart rhythm. Your veterinarian is the right person to provide guidance on the necessary duration of use and the most commonly considered monitoring schedule to ensure the management approach remains suitable for your pet's recovery.
Yes. Clarithromycin is a prescription antibiotic and can only be dispensed by a licensed pharmacy upon receipt of a valid authorization from a licensed veterinarian. Mixlab verifies all authorizations before any medication is prepared or shipped to your home.
Yes. While clarithromycin is available in commercial tablet and liquid formats for humans, Mixlab specializes in compounding the active ingredient into customized strengths and flavored dosage forms—such as flavored oral liquids—to suit the specific needs of dogs, cats and foals. The decision between a commercial and compounded product rests with the prescribing veterinarian.
Veterinarians frequently discuss clarithromycin for foals to manage serious respiratory infections caused by Rhodococcus equi. It is often paired with other medications to provide a comprehensive management approach for this specific bacterial challenge.
Localized digestive changes such as decreased appetite or vomiting are commonly observed effects of clarithromycin. Your veterinarian may recommend giving the medication with food to help manage these signs and ensure your pet remains comfortable during treatment.