ChloramPHENICOL/KETOconazole/Mupirocin/Triamcinolone clEARmix Lanolin Otic (3mL Syringe)
ChloramPHENICOL/KETOconazole/Mupirocin/Triamcinolone is a compounded formulation containing ChloramPHENICOL, KETOconazole, Mupirocin, Triamcinolone, prepared by Mixlab for veterinary use. Available by prescription.
How to Use clEARmix Lanolin Otic (Ear Medication)
This is a thick ear ointment used to treat ear infections. It comes in a pre-filled syringe with a soft tip, making it easier to apply and designed to stay in your pet’s ear longer.
Step-by-Step: 1. Warm the syringe – If it’s cold, hold it in your hands for a minute to soften the ointment. Do not microwave. 2. Position your pet – Have them sit in a comfy spot. You may need someone to gently help hold them. Lift their ear flap straight up. 3. Clean the ear (if needed) – Only if your vet told you to. Use a vet-approved ear cleaner and cotton ball—never a Q-tip deep in the ear. Let the ear dry. 4. Apply the medication – Remove the cap, then gently insert just the tip of the syringe into the ear opening. Don’t push in deep. 5. Dispense slowly – Press the plunger gently to apply the full dose or the amount your vet prescribed. 6. Massage the ear – Rub the base of the ear for about 30 seconds to help the medication spread. 7. Let them shake – It’s normal! Wipe off any excess with a tissue or cloth. 8. Reward your pet – Give them praise and maybe a treat to make it a positive experience. 9. Store the rest – If there’s more medication left, recap the syringe and store at room temp. Wash your hands after use.
This compounded formulation combines active ingredients from different drug classes: chloramphenicol, an antibiotic; ketoconazole, an azole antifungal; mupirocin, a topical antibiotic; and triamcinolone, a corticosteroid. In compounding practice, clinicians may consider a multi-ingredient preparation like this to address more than one aspect of a patient's physiology at once. Your veterinarian determines whether it is appropriate based on your animal's diagnostic findings.
This description reflects the general pharmacology of the active ingredient's drug class; your veterinarian determines whether this approach is appropriate for your animal.
Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring. Compounded drugs are not approved by the FDA for safety or effectiveness.
Commonly observed effects following the administration of this combination include localized changes at the application site, such as redness, itching or mild irritation. Because the formulation contains triamcinolone, systemic absorption is possible, especially with long-term use or application over large surface areas; your veterinarian will monitor for signs of corticosteroid influence such as increased thirst or changes in appetite. Owners should watch for behavioral shifts including excessive grooming of the site or unusual lethargy and contact their veterinarian promptly with any concerns.
This medication is typically used with extra caution or avoided in patients with known hypersensitivity to any of the active ingredients or those presented with viral skin infections. Because chloramphenicol is included in this prescription, humans handling the medication should follow specific safety precautions, such as wearing gloves during administration, as directed by their veterinarian. Before starting a protocol, ensure your veterinarian has a complete history of all other medications your pet is receiving. Your veterinarian is the right person to provide guidance on the necessary duration of use and the proper monitoring schedule to ensure the management approach remains suitable for your pet's recovery.
Yes. This quadruple-combination medication contains potent antibiotics, antifungals and steroids and can only be dispensed by a licensed pharmacy upon receipt of a valid authorization from a licensed veterinarian. Mixlab verifies all authorizations before any medication is prepared or shipped to your home.
Yes. Because this specific four-drug combination is not available as a single commercial product, Mixlab specializes in compounding it into customized strengths and vehicles—such as topical ointments or creams—to suit the specific needs of dogs and cats. The decision between a commercial and compounded preparation rests with the prescribing veterinarian.
Veterinarians discuss this combination because chloramphenicol and mupirocin target bacterial protein synthesis in different ways. Using both together allows the medication to address a broader spectrum of bacteria, including certain resistant strains, while the other ingredients manage concurrent fungus and inflammation.
Chloramphenicol requires careful handling; your veterinarian will recommend wearing unpowdered disposable gloves when applying the medication to your pet's skin. You should also wash your hands thoroughly after handling the medication and avoid direct contact with the addressed area until it has been fully absorbed by your pet's skin.
