Bravecto PLUS Topical Solution
Bravecto PLUS is an FDA-approved preparation containing Bravecto PLUS, for veterinary use. Available by prescription.
Veterinarians most commonly consider Bravecto® PLUS for patients where a comprehensive, long-acting parasite prevention strategy is required. It is frequently a point of discussion for cats with active outdoor lifestyles or those residing in environments with high exposure to fleas, ticks and heartworm vectors. By utilizing a dual-action pharmacological approach, your veterinarian can manage the risk of multiple parasitic infestations simultaneously.
The mechanism of action involves the synergistic properties of fluralaner and moxidectin. Fluralaner, a member of the isoxazoline class, acts as a potent inhibitor of the invertebrate nervous system by antagonizing ligand-gated chloride channels, specifically gamma-aminobutyric acid (GABA) and glutamate receptors. This help address the transmission of inhibitory signals in fleas and ticks, leading to hyperexcitation and death. Moxidectin, a semi-synthetic macrocyclic lactone, acts by binding to high-affinity glutamate-gated chloride channels. This increases membrane permeability to chloride ions, resulting in the paralysis and elimination of specific internal parasites, including heartworm larvae, hookworms and roundworms. Your veterinarian will determine the appropriateness of this medication based on your cat's weight, age and local heartworm prevalence.
The actions described here reflect the product's FDA-approved labeling; your veterinarian determines the appropriate use for your animal.
Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring.
Commonly observed effects following the administration of Bravecto® PLUS include localized skin reactions at the application site, such as hair loss, redness or itching. Some cats may exhibit digestive shifts, including vomiting or decreased appetite and behavioral changes such as lethargy have been noted. Because moxidectin is a systemic agent, it is a clinical priority for a veterinarian to perform a heartworm test before prescribing this medication, as the physiological response to the elimination of microfilariae in heartworm-positive cats can be significant.
As with other medications in the isoxazoline class, fluralaner has been associated with neurological events, including muscle tremors, ataxia and seizures. Your veterinarian will use caution when considering this product for cats with a known history of neurological disorders. Ensure that the product is applied topically and not ingested, as oral exposure may increase the frequency of adverse observations. Owners should monitor their pet for any unexpected physical or behavioral shifts and contact their veterinarian promptly with any concerns. Your veterinarian is the right person to provide guidance on the necessary duration of use and to assess any concurrent prescriptions your cat may be taking.
Yes. Bravecto® PLUS is a prescription-only medication and can only be dispensed by a licensed pharmacy upon receipt of a valid authorization from a licensed veterinarian. Mixlab verifies all veterinarian-client-patient relationships before shipping any medication.
Bravecto® PLUS is a proprietary commercial topical solution manufactured to strict stability and delivery standards. While Mixlab specializes in compounding many medications, this specific combination of fluralaner and moxidectin is dispensed in its original manufacturer-sealed applicators to ensure the integrity and efficacy of the long-acting formula.
Veterinarians discuss Bravecto® PLUS in the context of heartworm prevention because the moxidectin component targets heartworm larvae before they reach maturity. It is essential to consult your veterinarian for a heartworm test before starting this medication to ensure it is appropriate for your pet's current health status.
While many flea and tick medications require monthly application, veterinarians often consider Bravecto® PLUS for its extended duration, with many protocols directing application every two months. Your veterinarian will determine the exact schedule based on your cat’s individual risk factors and the specific parasites prevalent in your geographic area.
