Azathioprine Tablet
Azathioprine is available as an FDA-approved commercial product and as a compounded formulation, prepared by Mixlab for veterinary use in dogs. Available by prescription.
"The uses and pharmacology described below reflect the FDA-approved labeling for this active ingredient; your veterinarian determines whether and how they apply to your animal's treatment plan.
Azathioprine is an immunosuppressive agent that interferes with DNA synthesis in rapidly dividing cells, including certain immune cells. On the FDA-approved human label, it is indicated to help prevent organ transplant rejection and to manage certain inflammatory joint conditions.
In veterinary medicine, azathioprine is used off-label in dogs as part of managing certain immune-mediated conditions. Cats are far more sensitive to this drug's effects on bone marrow than dogs, and azathioprine is generally avoided in cats; your veterinarian determines whether this medication, and which species it's intended for, is appropriate. This information is not a substitute for veterinary diagnosis, prescribing, or monitoring. Compounded drugs are not approved by the FDA for safety or effectiveness."
Regular bloodwork, including a complete blood count and liver values, is typically recommended throughout treatment, since azathioprine can suppress bone marrow function and affect the liver. Effects can take several weeks to become fully apparent, and your veterinarian may use another medication in the meantime. Wear gloves when handling this medication, and avoid contact if you are pregnant or nursing. Contact your veterinarian if you notice unusual bruising, bleeding, lethargy, vomiting, or signs of infection.
Yes. Azathioprine is available only by prescription from a licensed veterinarian.
Both. Mixlab can dispense the FDA-approved commercial product, or compound the active ingredient into an alternative strength or format if your veterinarian determines that better suits your dog's needs. The decision rests with the prescribing veterinarian.
Azathioprine is generally avoided in cats due to heightened sensitivity to its effects on bone marrow. Your veterinarian determines the appropriate medication for your cat's condition.
Contact your veterinarian if you notice unusual bruising, bleeding, lethargy, vomiting, or signs of infection.
