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Atenolol/Enalapril Maleate  Oral Suspension (Anhydrous)

Atenolol/Enalapril Maleate Oral Suspension (Anhydrous)

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Atenolol/Enalapril Maleate is a compounded formulation containing atenolol (a beta-blocker) and enalapril (an ACE inhibitor), prepared by Mixlab for veterinary use. Available by prescription.

How to Give Anhydrous Oral Suspension

Oral Suspension (Anhydrous) is a liquid medication that does not contain water in its base. This might be an oil-based or other special base to help stabilize the medicine. It will look like a regular liquid medication, but often needs a good shake because the drug can settle. Here's how to give it:

  1. Shake well each time to mix the medication (5-10 seconds).
  2. Measure the dose using the syringe/dropper provided or one recommended by your vet. Insert the top of the oral syringe into the bottle adapter. Turn the bottle upside down and pull the plunger until the medicine reaches the volume required
  3. Hold your pet steady: a towel or helper can assist with squirmy pets.
  4. Administer the dose slowly into the side of the mouth. Allow small pauses if needed for swallowing.
  5. Raise the head slightly to help the medication go down and clean any spills with a little water or tissue.
  6. Praise your pet and offer a treat or water (unless advised against feeding right after).
  7. Clean the syringe with water immediately after use. Store the bottle as directed, out of sunlight.
  8. Consistency is key: Shake each time, measure accurately, and contact your vet if any issues arise.

This compounded formulation combines two cardiovascular agents from different drug classes: atenolol, a beta-adrenergic blocker and enalapril, an angiotensin-converting enzyme (ACE) inhibitor. In compounding practice, clinicians may consider a combination like this to consolidate two cardiovascular medications into a single administration. Your veterinarian determines whether it is appropriate based on your animal's cardiac evaluation and diagnostics.

Atenolol blocks beta-1 adrenergic receptors, which influences heart rate and the force of contraction; enalapril inhibits the ACE enzyme, reducing the production of angiotensin II and thereby influencing vascular tone and fluid balance.

This description reflects the general pharmacology of the active ingredient's drug class; your veterinarian determines whether this approach is appropriate for your animal.

Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring. Compounded drugs are not approved by the FDA for safety or effectiveness.

Because both ingredients affect the cardiovascular system, your veterinarian will individualize the preparation and monitor your animal, which may include blood pressure, kidney values and electrolytes. Do not stop abruptly without veterinary guidance. Provide a complete medication list so interactions can be considered.

Do I need a prescription for this?

Yes. This is a prescription product and can only be dispensed by a licensed pharmacy after a valid prescription is received from a licensed veterinarian. Mixlab verifies every prescription before dispensing.

Can this combination be compounded for my pet?

Yes. Mixlab can compound atenolol and enalapril together in a strength and format your veterinarian specifies for your animal.

Why combine a beta-blocker and an ACE inhibitor?

They act through different mechanisms on the cardiovascular system. Your veterinarian determines whether a combined preparation is appropriate for your animal.

What monitoring is involved?

Your veterinarian may monitor blood pressure, kidney values and electrolytes during use to keep the plan appropriate for your pet.

Mixlab is a licensed veterinary pharmacy dispensing both compounded and commercial medications, operating under the oversight of licensed pharmacists and in compliance with applicable state and federal pharmacy regulations. Compounded medications are prepared in compliance with USP standards and under PCAB-accredited practices. All medications dispensed by Mixlab require a valid prescription from a licensed veterinarian.
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