Amlodipine/MethimAZOLE/PredniSOLONE Oral Suspension (Anhydrous)
Amlodipine/Methimazole/Prednisolone is a compounded formulation containing amlodipine (a calcium channel blocker), methimazole (an antithyroid agent) and prednisolone (a corticosteroid), prepared by Mixlab for veterinary use. Available by prescription.
How to Give Anhydrous Oral Suspension
Oral Suspension (Anhydrous) is a liquid medication that does not contain water in its base. This might be an oil-based or other special base to help stabilize the medicine. It will look like a regular liquid medication, but often needs a good shake because the drug can settle. Here's how to give it:
- Shake well each time to mix the medication (5-10 seconds).
- Measure the dose using the syringe/dropper provided or one recommended by your vet. Insert the top of the oral syringe into the bottle adapter. Turn the bottle upside down and pull the plunger until the medicine reaches the volume required
- Hold your pet steady: a towel or helper can assist with squirmy pets.
- Administer the dose slowly into the side of the mouth. Allow small pauses if needed for swallowing.
- Raise the head slightly to help the medication go down and clean any spills with a little water or tissue.
- Praise your pet and offer a treat or water (unless advised against feeding right after).
- Clean the syringe with water immediately after use. Store the bottle as directed, out of sunlight.
- Consistency is key: Shake each time, measure accurately, and contact your vet if any issues arise.
This compounded formulation combines three active ingredients from different drug classes: amlodipine, a calcium channel blocker; methimazole, an antithyroid agent; and prednisolone, a corticosteroid. In compounding practice, clinicians may consider a combination like this — often as a flavored or transdermal preparation for cats — to consolidate more than one long-term medication into a single administration. Your veterinarian determines whether it is appropriate based on your animal's diagnostic findings.
Each ingredient acts through a distinct mechanism: amlodipine relaxes vascular smooth muscle by blocking calcium entry; methimazole inhibits the enzyme involved in thyroid hormone production; and prednisolone binds glucocorticoid receptors to modulate the inflammatory response.
This description reflects the general pharmacology of the active ingredient's drug class; your veterinarian determines whether this approach is appropriate for your animal.
Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring. Compounded drugs are not approved by the FDA for safety or effectiveness.
Because this preparation combines a cardiovascular agent, an antithyroid agent and a corticosteroid, your veterinarian will individualize it and monitor your animal, which may include periodic blood work. Give your veterinarian a complete medication list so interactions can be considered. If the formulation is transdermal, wear gloves when applying and rotate application sites as directed.
Yes. This is a prescription product and can only be dispensed by a licensed pharmacy after a valid prescription is received from a licensed veterinarian. Mixlab verifies every prescription before dispensing.
Yes. Mixlab can compound this combination in formats such as flavored liquids, chews or transdermal gels, as your veterinarian determines is appropriate for your pet.
Combining long-term medications into one preparation can simplify administration for some patients. Your veterinarian decides whether a combined product is appropriate for your animal.
If your veterinarian prescribes a transdermal form, wear gloves during application and wash your hands afterward. Keep the medication out of reach of children and other pets.
