Amikacin/KETOconazole/Triamcinolone clEARmix Lanolin Otic (3mL Syringe)
Amikacin/Ketoconazole/Triamcinolone is a compounded topical formulation that combines an antibiotic (amikacin), an antifungal (ketoconazole), and a corticosteroid (triamcinolone). It is commonly used in dogs (and sometimes cats) as an otic solution for ears or as a skin preparation, applied directly to the affected area.
How to Use clEARmix Lanolin Otic (Ear Medication)
This is a thick ear ointment used to treat ear infections. It comes in a pre-filled syringe with a soft tip, making it easier to apply and designed to stay in your pet’s ear longer.
Step-by-Step: 1. Warm the syringe – If it’s cold, hold it in your hands for a minute to soften the ointment. Do not microwave. 2. Position your pet – Have them sit in a comfy spot. You may need someone to gently help hold them. Lift their ear flap straight up. 3. Clean the ear (if needed) – Only if your vet told you to. Use a vet-approved ear cleaner and cotton ball—never a Q-tip deep in the ear. Let the ear dry. 4. Apply the medication – Remove the cap, then gently insert just the tip of the syringe into the ear opening. Don’t push in deep. 5. Dispense slowly – Press the plunger gently to apply the full dose or the amount your vet prescribed. 6. Massage the ear – Rub the base of the ear for about 30 seconds to help the medication spread. 7. Let them shake – It’s normal! Wipe off any excess with a tissue or cloth. 8. Reward your pet – Give them praise and maybe a treat to make it a positive experience. 9. Store the rest – If there’s more medication left, recap the syringe and store at room temp. Wash your hands after use.
This compounded formulation combines three active ingredients from different drug classes: amikacin, an aminoglycoside antibiotic; ketoconazole, an azole antifungal; and triamcinolone, a corticosteroid. In compounding practice, clinicians may consider a combination like this for a localized, multi-targeted approach. Your veterinarian determines whether it is appropriate based on your animal's diagnostic findings and culture or cytology results.
Each ingredient acts through a distinct mechanism: amikacin binds to the 30S bacterial ribosomal subunit to interfere with bacterial protein synthesis; ketoconazole inhibits fungal ergosterol synthesis, affecting the fungal cell membrane; and triamcinolone binds cytoplasmic glucocorticoid receptors to modulate inflammatory mediators.
This description reflects the general pharmacology of the active ingredient's drug class; your veterinarian determines whether this approach is appropriate for your animal.
Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring. Compounded drugs are not approved by the FDA for safety or effectiveness.
Because this preparation contains an antibiotic, an antifungal and a corticosteroid, your veterinarian will tailor it to your animal's specific situation and monitor the response. Give your veterinarian a complete list of your pet's other medications so interactions can be considered. Follow the application instructions carefully and contact your veterinarian if the area worsens or does not respond.
Yes. This is a prescription product and can only be dispensed by a licensed pharmacy after a valid prescription is received from a licensed veterinarian. Mixlab verifies every prescription before dispensing.
Yes. Mixlab can compound this three-ingredient combination in the strength and format your veterinarian specifies for your animal.
Each active contributes a different mechanism — antibacterial, antifungal and anti-inflammatory. Your veterinarian determines whether a combined preparation is appropriate for your animal's situation.
Follow the dispensing label and your veterinarian's instructions, wash your hands after applying and keep it out of reach of children and other animals.
