
Altrenogest is an oral solution containing the progestin altrenogest, for veterinary use in horses. Available by prescription.
Giving your pet an injection might feel intimidating at first, but with practice, it becomes routine. Follow these steps for safe and stress-free injections.
Get Your Supplies Ready
Drawing Up the Dose (if needed)
Pick the Injection Site
Prep the Area
Inject the Medication
After the Injection
Safety Tips
Altrenogest is an FDA-approved product for horses. According to the FDA-approved labeling, it is used to suppress estrus (heat) in mares. Veterinarians may also discuss it for synchronizing estrus within a group of mares. Your veterinarian determines the appropriate use for your horse.
At a pharmacological level, altrenogest is a progestin that mimics the effects of progesterone. It binds to progesterone receptors, which suppresses the release of gonadotropins from the pituitary gland; this inhibits follicle maturation and the onset of estrus. When the medication is discontinued, mares typically return to a predictable cycle.
The actions described here reflect the product's FDA-approved labeling; your veterinarian determines the appropriate use for your animal.
Prescription only. Use only under the direction of a licensed veterinarian. This information is not a substitute for veterinary diagnosis, prescribing or monitoring.
Altrenogest is associated with specific safety considerations for both the animal and the person administering the medication. Commonly observed effects in horses are minimal, though some individuals may exhibit mild changes in temperament or site-specific reactions if an injectable form is utilized. It is essential to consult your veterinarian if your mare has a history of uterine inflammation or infection, as progestins can potentially mask or exacerbate these conditions.
A critical aspect of using altrenogest is human safety, as the medication can be absorbed through the skin. Pregnant women or individuals with a history of certain hormone-dependent conditions should avoid direct contact with the product. Non-porous protective gloves (such as chemical-resistant nitrile or neoprene) are a standard recommendation during administration to prevent accidental exposure. Your veterinarian will provide comprehensive guidance on safe handling and any necessary monitoring for your horse. Contact your veterinarian promptly if you observe any unexpected physical or behavioral changes in your mare while she is receiving this prescription.
Yes. Altrenogest is a prescription medication and can only be dispensed by a licensed pharmacy upon receipt of a valid prescription from a licensed veterinarian. Mixlab verifies authorization for all prescriptions before they are dispensed.
Altrenogest is available as a commercial oral solution, but it can also be compounded into alternative strengths or formulations when a veterinarian determines that a custom preparation is clinically necessary. Mixlab’s compounding team works closely with your veterinarian to provide the most appropriate format for your horse.
Altrenogest maintains a consistent hormonal state by suppressing estrus, which is its FDA-approved indication. Your veterinarian determines whether this is appropriate for a mare in performance or competition.
Yes, because altrenogest is a hormone that can be absorbed through human skin, it must be handled with extreme care. Veterinarians recommend wearing non-porous gloves during administration and suggest that individuals who are pregnant or have certain medical histories avoid handling the medication entirely.